STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2134Conserved hypothetical protein; N-terminus similar to those from other actinomycetes eg. Saccharopolyspora erythraea Orf122 protein TR:Q54106 (EMBL:X92556) (121 aa) fasta scores: E(): 0.0076, 31.15% id in 138 aa, and to Streptomyces coelicolor hypothetical 30.8 kDa protein SCE6.30c TR:Q9KZR0 (EMBL:AL353832) (277 aa) fasta scores: E(): 0.02, 36.76% id in 68 aa. (206 aa)    
Predicted Functional Partners:
DIP2264
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 123.1 kDa protein Rv1251c or MT1290 or MTV006.23c SWALL:O50466 (EMBL:AL021006) (1139 aa) fasta scores: E(): 1.6, 26.47% id in 544 aa.
  
     0.740
DIP2269
Hypothetical protein; No significant database matches.
  
     0.715
DIP0688
Conserved hypothetical protein; Similar in its N-terminal region to Mycobacterium tuberculosis hypothetical 35.3 kDa protein Rv3256c or MTV015.01c or MTCY20b11.31c TR:O05899 (EMBL:Z95121) (346 aa) fasta scores: E(): 5.1e-06, 27.69% id in 260 aa.
  
     0.708
DIP1995
Putative membrane protein; Weakly similar to the N-terminal regions of Mycobacterium leprae putative membrane protein ML0228 TR:O69526 (EMBL:AL023093) (432 aa) fasta scores: E(): 0.025, 25.15% id in 318 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3709 TR:AAK48067 (EMBL:AE007170) (397 aa) fasta scores: E(): 0.071, 23.51% id in 336 aa.
  
     0.708
DIP2133
Putative conserved membrane protein; Similar to many eg. Mycobacterium tuberculosis hypothetical 95.5 kDa protein Rv0338c or MT0352 or MTCY279.05C TR:O33268 (EMBL:Z97991) (882 aa) fasta scores: E(): 2.4e-55, 43.1% id in 877 aa. N-terminal region appears to be has possible membrane-spanning hydrophobic regions while the C-terminal region is rich in proline and alanine.
       0.708
DIP1352
Hypothetical protein; No significant database matches.
  
     0.680
DIP0246
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 17.9 kDa protein Rv3753c or MTV025.10c TR:O69720 (EMBL:AL022121) (166 aa) fasta scores: E(): 1e-20, 45.57% id in 147 aa; Conserved hypothetical protein.
  
     0.671
DIP1842
Putative membrane protein; Poor database matches. Similar to Mycobacterium tuberculosis hypothetical protein Rv2520c TR:O53225 (EMBL:AL021185) (75 aa) fasta scores: E(): 2.7e-06, 45.33% id in 75 aa.
  
     0.650
DIP1912
Putative secreted protein; Poor database matches. Similar to Mycobacterium leprae probable exported protein ML2195 TR:Q50040 (EMBL:U15182) (283 aa) fasta scores: E(): 0.44, 23.39% id in 265 aa.
  
     0.636
DIP2067
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 25.3 kDa protein ML0281 or MLCB4.24 SWALL:O69596 (EMBL:AL023514) (229 aa) fasta scores: E(): 6.1e-08, 36.63% id in 202 aa.
  
     0.620
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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