STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2135Similar to Neisseria meningitidis putative zinc-binding alcohol dehydrogenase NMA0808 TR:Q9JVJ8 (EMBL:AL162754) (354 aa) fasta scores: E(): 1.1e-85, 64.62% id in 359 aa, and to Bacillus cereus acetylacetoin reductase AacR TR:BAB60856 (EMBL:AB063194) (349 aa) fasta scores: E(): 5.6e-47, 42.25% id in 355 aa, and to Pseudomonas putida 2,3-butanediol dehydrogenase Adh TR:Q59696 (EMBL:L35343) (362 aa) fasta scores: E(): 6.6e-40, 37.63% id in 364 aa. (363 aa)    
Predicted Functional Partners:
DIP0990
Putative decarboxylase (internal pH control related); Similar to Bacillus subtilis alpha-acetolactate decarboxylase AlsD SW:ALDC_BACSU (Q04777) (255 aa) fasta scores: E(): 2.1e-38, 44.78% id in 230 aa.
     
 0.965
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
  
  
 0.685
adhA
Similar to Rhizobium meliloti alcohol dehydrogenase AdhA or RA0704 or SMA1296 SWALL:ADHA_RHIME (SWALL:O31186) (340 aa) fasta scores: E(): 1.4e-71, 55.09% id in 334 aa, and to Pseudomonas aeruginosa alcohol dehydrogenase AdhA or PA5427 SWALL:Q9HTD9 (EMBL:AE004955) (342 aa) fasta scores: E(): 1.5e-79, 58.99% id in 339 aa.
 
 
 0.609
DIP1382
Putative aminotransferase (biotin synthesis related protein); Similar to Bacillus sphaericus 8-amino-7-oxononanoate synthase BioF SWALL:BIOF_BACSH (SWALL:P22806) (389 aa) fasta scores: E(): 8.9e-47, 40.95% id in 376 aa, and to Escherichia coli 8-amino-7-oxononanoate synthase BioF or B0776 SWALL:BIOF_ECOLI (SWALL:P12998) (384 aa) fasta scores: E(): 9.8e-39, 37.39% id in 353 aa.
  
  
 0.503
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
  
  
 0.498
DIP2136
Putative aminotransferase; Similar to Mycobacterium tuberculosis probable aspartate aminotransferase AspC or Rv0337c or MT0351 or MTCY279.04c SW:AAT_MYCTU (O33267) (429 aa) fasta scores: E(): 2.4e-120, 71.32% id in 415 aa, and to Escherichia coli probable aminotransferase YfbQ or B2290 SW:YFBQ_ECOLI (P77727) (405 aa) fasta scores: E(): 1.8e-101, 61.59% id in 401 aa, and to Methylobacillus flagellatum aspartate aminotransferase Aat TR:Q9RAN0 (EMBL:L78665) (429 aa) fasta scores: E(): 1.7e-87, 55.08% id in 403 aa.
  
  
 0.470
DIP2009
Putative peptide synthase; N-terminal region similar to C-terminal region of Streptomyces lavendulae peptide synthetase SWALL:AAK81825 (EMBL:AF386507) (1531 aa) fasta scores: E(): 1.3e-38, 34.02% id in 814 aa, similar in its full length to Agrobacterium tumefaciens StrC58 AGR_l_3476p SWALL:AAK90311 (EMBL:AE008376) (1344 aa) fasta scores: E(): 6.2e-36, 32.96% id in 1338 aa, and N-terminal region similar to the full length of Amycolatopsis orientalis PCZA361.18 SWALL:O52803 (EMBL:AJ223998) (580 aa) fasta scores: E(): 1.3e-33, 38.2% id in 589 aa. C-terminal region presents low similarity [...]
  
  
 0.437
DIP0427
Similar to Clostridium acetobutylicum lactate dehydrogenase CAC3552 TR:AAK81477 (EMBL:AE007851) (320 aa) fasta scores: E(): 1.6e-36, 38.6% id in 316 aa, and to Bacillus subtilis L-lactate dehydrogenase Ldh or LctE SW:LDH_BACSU (P13714) (320 aa) fasta scores: E(): 2.9e-25, 33.95% id in 324 aa; Belongs to the LDH/MDH superfamily.
   
 
 0.425
DIP0361
Putative bifunctional protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
     
 0.422
gbsA
Similar to Bacillus subtilis betaine aldehyde dehydrogenase GbsA SW:DHAB_BACSU (P71016) (490 aa) fasta scores: E(): 2e-73, 54.63% id in 496 aa, and to Streptomyces coelicolor betaine aldehyde dehydrogenase GbsA TR:Q9K3J2 (EMBL:AL389898) (509 aa) fasta scores: E(): 3.2e-88, 55.75% id in 504 aa.
  
 
 0.406
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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