STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2137Similar to Streptomyces coelicolor putative membrane protein SCQ11.10c TR:Q9X9U1 (EMBL:AL096823) (513 aa) fasta scores: E(): 2.1e-35, 37.59% id in 383 aa, and to Pseudomonas aeruginosa sensor protein GlpS or pa1977 SW:GLPS_PSEAE (P29370) (287 aa) fasta scores: E(): 2.5, 29.41% id in 238 aa. (385 aa)    
Predicted Functional Partners:
lysS
Appears to be a gene fusion. N-terminal region similar to Streptomyces coelicolor putative integral membrane protein SC3C8.03c TR:O69916 (EMBL:AL023861) (589 aa) fasta scores: E(): 4.3e-57, 37.26% id in 577 aa. C-terminal region similar to Thermus aquaticus lysyl-tRNA synthetase LysS SW:SYK_THETH (P41255) (492 aa) fasta scores: E(): 9.8e-57, 40.8% id in 446 aa; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.706
DIP2136
Putative aminotransferase; Similar to Mycobacterium tuberculosis probable aspartate aminotransferase AspC or Rv0337c or MT0351 or MTCY279.04c SW:AAT_MYCTU (O33267) (429 aa) fasta scores: E(): 2.4e-120, 71.32% id in 415 aa, and to Escherichia coli probable aminotransferase YfbQ or B2290 SW:YFBQ_ECOLI (P77727) (405 aa) fasta scores: E(): 1.8e-101, 61.59% id in 401 aa, and to Methylobacillus flagellatum aspartate aminotransferase Aat TR:Q9RAN0 (EMBL:L78665) (429 aa) fasta scores: E(): 1.7e-87, 55.08% id in 403 aa.
       0.651
DIP2171
Putative exported protein; No significant database matches.
  
     0.501
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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