Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP2140Putative integral membrane protein; Weakly similar to Lactococcus lactis unknown protein YldA or ll1118 TR:Q9CGH8 (EMBL:AE006344) (209 aa) fasta scores: E(): 0.092, 24% id in 175 aa. (206 aa)    
Predicted Functional Partners:
DIP2139
Hypothetical protein; No significant database matches.
       0.800
DIP2141
Similar to Streptomyces coelicolor putative UDP-glucose 6-dehydrogenase SCBAC19G2.07 TR:CAC44517 (EMBL:AL596138) (447 aa) fasta scores: E(): 2.8e-33, 40.75% id in 422 aa, and to Pseudomonas aeruginosa UDP-glucose 6-dehydrogenase Udg or pa2022 SW:UDG_PSEAE (O86422) (453 aa) fasta scores: E(): 1.9e-26, 39.66% id in 358 aa, and to Rhizobium meliloti UDP-glucose 6-dehydrogenase Rkpk or r01082 or smc02641 SW:UDG_RHIME (O54068) (437 aa) fasta scores: E(): 8.9e-26, 37.71% id in 411 aa, and to Escherichia coli UDP-glucose 6-dehydrogenase KfiD SW:UDG5_ECOLI (Q47329) (392 aa) fasta scores: E(): [...]
       0.701
dcd
Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
       0.701
repA
Putative IS element transposase (pseudogene); Pseudogene. Similar to although shorter in its N-terminal region than Shigella flexneri putative transposase for IS110 S0128 SWALL:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 1.6e-18, 40.55% id in 254 aa, and similar to Streptomyces coelicolor putative IS element transposase SC3C8.17 SWALL:O69929 (EMBL:AL023861) (230 aa) fasta scores: E(): 7.9e-18, 45.61% id in 171 aa. Presents multiple frameshifts at residues 84, 125, 130, 145, 150 and 180.
  
     0.644
lysS
Appears to be a gene fusion. N-terminal region similar to Streptomyces coelicolor putative integral membrane protein SC3C8.03c TR:O69916 (EMBL:AL023861) (589 aa) fasta scores: E(): 4.3e-57, 37.26% id in 577 aa. C-terminal region similar to Thermus aquaticus lysyl-tRNA synthetase LysS SW:SYK_THETH (P41255) (492 aa) fasta scores: E(): 9.8e-57, 40.8% id in 446 aa; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
     0.619
DIP0238
Putative surface-anchored fimbrial subunit; Weak similarity to Actimomyces fimbrial associated protein. Note: Contains a potential sortase anchor site (LPKTG) upstream of the C-terminal region transmembrane domain.
  
     0.587
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
  
 
 0.583
DIP0906
Putative membrane protein; Low similarity to Streptomyces coelicolor putative integral membrane protein SCI35.39 TR:O88074 (EMBL:AL031541) (394 aa) fasta scores: E(): 1.8e-16, 29.34% id in 351 aa.
  
     0.582
DIP1200
Putative membrane protein; Similar to Corynebacterium glutamicum hypothetical 45.7 kDa protein in lysI 3'region SWALL:YLI2_CORGL (SWALL:P35866) (426 aa) fasta scores: E(): 4.7e-68, 46.93% id in 424 aa, and to Mycobacterium tuberculosis hypothetical 51.8 kDa protein Rv1639c or MTCY06H11.03c SWALL:P94973 (EMBL:Z85982) (489 aa) fasta scores: E(): 1.8e-16, 23.89% id in 385 aa.
  
     0.513
DIP1117
Putative TetR-family transcriptional regulator; Similar to Streptomyces coelicolor SC10A5.11 protein TR:O54102 (EMBL:AL021529) (198 aa) fasta scores: E(): 8.8e-14, 32.94% id in 170 aa, and to Streptomyces roseosporus WhiR protein TR:P72569 (EMBL:U58281) (179 aa) fasta scores: E(): 1.5e-05, 24.5% id in 151 aa.
  
     0.466
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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