STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2141Similar to Streptomyces coelicolor putative UDP-glucose 6-dehydrogenase SCBAC19G2.07 TR:CAC44517 (EMBL:AL596138) (447 aa) fasta scores: E(): 2.8e-33, 40.75% id in 422 aa, and to Pseudomonas aeruginosa UDP-glucose 6-dehydrogenase Udg or pa2022 SW:UDG_PSEAE (O86422) (453 aa) fasta scores: E(): 1.9e-26, 39.66% id in 358 aa, and to Rhizobium meliloti UDP-glucose 6-dehydrogenase Rkpk or r01082 or smc02641 SW:UDG_RHIME (O54068) (437 aa) fasta scores: E(): 8.9e-26, 37.71% id in 411 aa, and to Escherichia coli UDP-glucose 6-dehydrogenase KfiD SW:UDG5_ECOLI (Q47329) (392 aa) fasta scores: E(): [...] (401 aa)    
Predicted Functional Partners:
DIP0361
Putative bifunctional protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
  
 0.964
DIP0862
Putative urydyltransferase; Similar to Mycobacterium tuberculosis CDC1551 UTP--glucose-1-phosphate uridylyltransferase MT1022 TR:AAK45269 (EMBL:AE006986) (306 aa) fasta scores: E(): 3.2e-65, 64.8% id in 287 aa, and to Bacillus subtilis UTP--glucose-1-phosphate uridylyltransferase GtaB SW:GTAB_BACSU (Q05852) (292 aa) fasta scores: E(): 1.4e-32, 40.67% id in 295 aa.
 
 0.964
galE
UDP-glucose 4-epimerase; Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity).
 
 
 0.933
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
  
 0.884
rmlB
Similar to Mycobacterium leprae putative dTDP-(glucose or rhamnose)-4,6-dehydratase RmlB TR:Q9X7A3 (EMBL:AL049491) (331 aa) fasta scores: E(): 8.3e-84, 63.77% id in 334 aa; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
  
 0.867
dcd
Deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
       0.842
galT
Similar to Escherichia coli galactose-1-phosphate uridylyltransferase GalT or GalB or B0758 SW:GAL7_ECOLI (P09148) (348 aa) fasta scores: E(): 1.2e-24, 30.34% id in 346 aa, and to Streptomyces lividans galactose-1-phosphate uridylyltransferase GalT SW:GAL7_STRLI (P13212) (354 aa) fasta scores: E(): 4.9e-30, 38.8% id in 384 aa, and to Homo sapiens galactose-1-phosphate uridylyltransferase GalT SW:GAL7_HUMAN (P07902) (379 aa) fasta scores: E(): 8.1e-29, 33.82% id in 340 aa.
    
  0.812
glf
Similar to Escherichia coli UDP-galactopyranose mutase Glf or B2036 SW:GLF_ECOLI (P37747) (367 aa) fasta scores: E(): 5.4e-48, 45.35% id in 377 aa, and to Mycobacterium tuberculosis UDP-galactopyranose mutase Glf or Rv3809c or MTV026.14 TR:O06934 (EMBL:U96128) (399 aa) fasta scores: E(): 1.3e-121, 76.09% id in 389 aa.
  
  
 0.806
DIP2139
Hypothetical protein; No significant database matches.
       0.701
DIP2140
Putative integral membrane protein; Weakly similar to Lactococcus lactis unknown protein YldA or ll1118 TR:Q9CGH8 (EMBL:AE006344) (209 aa) fasta scores: E(): 0.092, 24% id in 175 aa.
       0.701
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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