STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2153Similar to Bacteriophage phi-105 holin TR:Q38456 (EMBL:L35561) (124 aa) fasta scores: E(): 5.4e-14, 41.22% id in 114 aa, and to Escherichia coli O157:H7 putative holin protein of prophage cp-933c Z1852 or ECS1595 TR:AAG55949 (EMBL:AE005328) (129 aa) fasta scores: E(): 1.7e-07, 40.77% id in 103 aa. (125 aa)    
Predicted Functional Partners:
DIP2154
Putative DNA-binding bacteriophage protein; Similar to Xylella fastidiosa phage-related protein XF0684 TR:Q9PFH4 (EMBL:AE003912) (503 aa) fasta scores: E(): 1.8e-13, 56.52% id in 92 aa, and to Lactobacillus casei bacteriophage A2 putative Antirepressor Ant TR:O64368 (EMBL:AJ251789) (160 aa) fasta scores: E(): 2.9e-08, 36.69% id in 139 aa, and to Bacteriophage r1t integrase, repressor protein TR:Q38091 (EMBL:U38906) (265 aa) fasta scores: E(): 2.3e-06, 36.98% id in 219 aa.
 
     0.939
DIP0203
Putative phage terminase (pseudogene); ProfileScan hit to PS50312, Aspartic acid-rich region.
 
    0.695
DIP1834
Putative phage protein; Similar to Bacteriophage r1t ORF40 TR:Q38126 (EMBL:U38906) (213 aa) fasta scores: E(): 0.019, 25.904% id in 166 aa, and to Escherichia coli O157:H7 putative tail length tape measure protein precursor ECS2949 TR:BAB36372 (EMBL:AP002560) (881 aa) fasta scores: E(): 0.025, 27.698% id in 278 aa.
 
    0.619
DIP2152
Putative transposase (pseudogene); Predicted helix-turn-helix motif with score 1004 (+2.61 SD) at aa 6-27, sequence LGVRAIARHWGRSPGTISKEMT.
       0.547
DIP0212
Immunity-specific protein Beta241; C-terminal region identical to Corynephage beta immunity-specific protein Beta241 TR:Q37919 (EMBL:L04258) (241 aa) fasta scores: E(): 3.1e-64, 100% id in 241 aa, and whole length similar to Staphylococcus aureus subspaureus Mu50 phi pvl ORF15 and 16 homologue SAV1955 TR:BAB58117 (EMBL:AP003364) (1509 aa) fasta scores: E(): 2.9e-19, 23.76% id in 1073 aa.
 
     0.473
DIP0190
Putative anti-repressor protein; Similar to Staphylococcus aureus prophage phiPV83 antirepressor TR:Q9MBT0 (EMBL:AB044554) (265 aa) fasta scores: E(): 1.5e-32, 42.8% id in 257 aa.
 
     0.461
DIP2155
Similar to Pasteurella multocida hypothetical protein Pm1783 TR:Q9CK51 (EMBL:AE006215) (316 aa) fasta scores: E(): 1.4e-26, 32.226% id in 301 aa, and to Staphylococcus aureus subspaureus Mu50. hypothetical 38.5 kDa protein Sav0801 TR:BAB56963 (EMBL:AP003360) (322 aa) fasta scores: E(): 2.7e-07, 22.876% id in 306 aa.
       0.444
DIP0238
Putative surface-anchored fimbrial subunit; Weak similarity to Actimomyces fimbrial associated protein. Note: Contains a potential sortase anchor site (LPKTG) upstream of the C-terminal region transmembrane domain.
  
     0.430
DIP1724
Putative surface-anchored membrane protein; No significant database matches. Note: Contains a potential sortase anchor site (LANTG) upstream of the C-terminal region transmembrane domain. Contains also a putative twin-arginine translocation (TAT) system recognition motif (RRVFAS) at the N-terminal region. Also similar to DIP0439, DIP0442, DIP2325 and DIP0443.
  
     0.421
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.