STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2159ABC transport protein; Similar to Yersinia enterocolitica lipoprotein inner membrane ABC-transporter, Irp6 TR:Q9X9I5 (EMBL:AJ132668) (600 aa) fasta scores: E(): 2.5e-43, 34.286% id in 560 aa, and to Streptomyces natalensis PimB protein TR:Q9EW97 (EMBL:AJ278573) (626 aa) fasta scores: E(): 3e-37, 32.519% id in 532 aa. (593 aa)    
Predicted Functional Partners:
opuBA
Similar to Bacillus subtilis choline transport ATP-binding protein OpuBA or ProV SW:OPBA_BACSU (Q45460) (381 aa) fasta scores: E(): 2.5e-42, 50.58% id in 255 aa, and to Mycobacterium tuberculosis putative ABC transporter ATP-binding protein Rv3758c or MTV025.106c TR:O69724 (EMBL:AL022121) (376 aa) fasta scores: E(): 1.3e-42, 53.62% id in 248 aa.
 
    
0.903
DIP0448
Similar to Streptomyces coelicolor putative ABC transport system ATP-binding protein SCE41.20c TR:Q9F2N9 (EMBL:AL442120) (262 aa) fasta scores: E(): 2.4e-29, 44.49% id in 236 aa.
 
    
0.890
DIP2158
Pseudogene. Similar to C-terminus of Bacteriophage SP02 DNA polymerase L SWALL:DPOL_BPSP2 (SWALL:P06225) (648 aa) fasta scores: E(): 1.3e-34, 50.61% id in 245 aa, and to Xylella fastidiosa phage-related DNA polymerase XF0683 SWALL:Q9PFH5 (EMBL:AE003912) (726 aa) fasta scores: E(): 6e-19, 32.49% id in 277 aa. Presents a frameshift at residue 46.
 
    
0.879
DIP2161
Nonribosomal peptide synthase; Similar to Stigmatella aurantiaca myxothiazol synthase MtaC TR:Q9RFK9 (EMBL:AF188287) (1290 aa) fasta scores: E(): 1.7e-86, 35.694% id in 1073 aa, and to Polyangium cellulosum epothilone biosynthase EpoB TR:Q9KIZ9 (EMBL:AF217189) (1410 aa) fasta scores: E(): 1.8e-81, 35.385% id in 975 aa, and to Pseudomonas aeruginosa pyochelin synthetase PchF or PA4225 TR:Q9HWG4 (EMBL:AE004839) (1809 aa) fasta scores: E(): 1.9e-81, 37.017% id in 932 aa.
 
 
 0.865
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
 
 0.849
atrC
Putative ABC transport system ATP-binding protein; Similar to Streptomyces coelicolor ATP-binding protein AtrC SWALL:Q9F3K7 (EMBL:AL391763) (253 aa) fasta scores: E(): 5.1e-58, 68% id in 250 aa, and to Rhizobium sp TAL1145 MidC SWALL:Q9EYT0 (EMBL:AF312768) (265 aa) fasta scores: E(): 1.9e-52, 60.78% id in 255 aa.
 
     
0.836
DIP0754
Putative lantibiotic ABC-transport system membrane protein; Similar to Staphylococcus aureus transporter TR:Q9S4D0 (EMBL:AF147744) (720 aa) fasta scores: E(): 2.4e-57, 29.986% id in 707 aa, and to Lactococcus lactis cytolysin B transport protein TR:O87239 (EMBL:AE001272) (708 aa) fasta scores: E(): 7.1e-55, 28.571% id in 714 aa.
 
 
  
0.694
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.627
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
   0.501
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
  
 
 0.498
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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