Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP2174Similar to Mycobacterium leprae possible integral membrane protein ML2570 TR:Q9CD19 (EMBL:AL583926) (1405 aa) fasta scores: E(): 2.5e-17, 37.3% id in 823 aa, and to Mycobacterium tuberculosis hypothetical 146.3 kDa protein Rv0236c or MT0247 or MTV034.01c or MTV034.02c or MTCY08D5.32c TR:AAK44467 (EMBL:Z92669) (1400 aa) fasta scores: E(): 7.4e-17, 38.32% id in 822 aa. ORF overlaps with convergent downstream ORF. (1025 aa)    
Predicted Functional Partners:
DIP1690
Putative membrane protein; Similar to Mycobacterium leprae hypothetical 50.2 kDa protein ML1338 or MLC1351.25 TR:O05686 (EMBL:Z95117) (440 aa) fasta scores: E(): 1.8e-11, 29.77% id in 393 aa.
  
  
 0.977
DIP2177
Putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 59.1 kDa protein Rv0226c or MTCY08D5.21c TR:P96408 (EMBL:Z92669) (576 aa) fasta scores: E(): 6e-08, 30% id in 530 aa. ORF overlaps with convergent downstream ORF.
 
   
 0.875
DIP2173
Putative secreted protein; Similar to Mycobacterium tuberculosis putative secreted protein Rv0236.1 precursor or Rv0236A or MT0250 SW:Y23A_MYCTU (P58240) (57 aa) fasta scores: E(): 0.39, 32.72% id in 55 aa.
     
 0.841
DIP2179
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.5 kDa protein Rv0224c or MTCY08D5.19c TR:P96406 (EMBL:Z92669) (254 aa) fasta scores: E(): 2.9e-56, 63.41% id in 246 aa, and to Streptomyces coelicolor putative methyltransferase SCC53.08c TR:Q9KXK3 (EMBL:AL357591) (244 aa) fasta scores: E(): 7.1e-06, 32.94% id in 173 aa.
     0.823
fas
Putative fatty acid synthase; Similar to the N-terminal region of Corynebacterium ammoniagenes fatty acid synthase Fas TR:Q04846 (EMBL:X64795) (3104 aa) fasta scores: E(): 0, 61.33% id in 3018 aa, and to the full length of Mycobacterium tuberculosis fatty acid synthase Rv2524c TR:AAK46907 (EMBL:Z83863) (3069 aa) fasta scores: E(): 1e-197, 51.37% id in 3083 aa, and of Corynebacterium glutamicum 3-oxoacyl-(acyl-carrier-protein) synthase CGL2495 SWALL:Q8NMS0 (EMBL:AP005281) (2993 aa) fasta scores: E(): 0, 67.35% id in 3008 aa.
 
  
 0.781
DIP0445
Putative membrane protein; Low similarity to Mycobacterium leprae putative integral membrane protein ML2581 TR:Q9CD18 (EMBL:AL583926) (427 aa) fasta scores: E(): 2.5, 24.7% id in 344 aa.
 
     0.780
DIP0160
Putative membrane protein; Similar to Mycobacterium tuberculosis hypothetical 69.5 kDa protein CY13D12.26 Rv3792 or MTCY13D12.26 TR:P72058 (EMBL:Z80343) (643 aa) fasta scores: E(): 3.7e-53, 34.5% id in 652 aa.
  
   
 0.779
DIP2178
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 42.1 kDa protein Rv0225 or MTCY08D5.20 TR:P96407 (EMBL:Z92669) (384 aa) fasta scores: E(): 3.5e-62, 51.48% id in 371 aa. ORF overlaps with convergent downstream ORF.
 
   
 0.753
DIP2176
Similar to Mycobacterium leprae putative integral membrane protein Ml2581 TR:Q9CD18 (EMBL:AL583926) (427 aa) fasta scores: E(): 8.6e-14, 27.79% id in 367 aa.
 
   
 0.740
DIP2172
Similar to Mycobacterium leprae putative secreted glycosyl hydrolase ML2569 or MLCB1883.14 TR:O69499 (EMBL:AL022486) (387 aa) fasta scores: E(): 3e-40, 42.33% id in 385 aa, and to Vibrio furnissii beta-hexosaminidase NagZ or Exo II SW:NAGZ_VIBFU (P96157) (329 aa) fasta scores: E(): 9e-13, 30.94% id in 265 aa. Note: Contains a putative twin-arginine translocation (TAT) system recognition motif (RRVFTP) at the N-terminal region.
     
 0.705
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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