STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2177Putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 59.1 kDa protein Rv0226c or MTCY08D5.21c TR:P96408 (EMBL:Z92669) (576 aa) fasta scores: E(): 6e-08, 30% id in 530 aa. ORF overlaps with convergent downstream ORF. (470 aa)    
Predicted Functional Partners:
DIP2176
Similar to Mycobacterium leprae putative integral membrane protein Ml2581 TR:Q9CD18 (EMBL:AL583926) (427 aa) fasta scores: E(): 8.6e-14, 27.79% id in 367 aa.
 
   
 0.966
DIP2174
Similar to Mycobacterium leprae possible integral membrane protein ML2570 TR:Q9CD19 (EMBL:AL583926) (1405 aa) fasta scores: E(): 2.5e-17, 37.3% id in 823 aa, and to Mycobacterium tuberculosis hypothetical 146.3 kDa protein Rv0236c or MT0247 or MTV034.01c or MTV034.02c or MTCY08D5.32c TR:AAK44467 (EMBL:Z92669) (1400 aa) fasta scores: E(): 7.4e-17, 38.32% id in 822 aa. ORF overlaps with convergent downstream ORF.
 
   
 0.949
DIP2175
Putative integral membrane acyltransferase; Similar to Mycobacterium tuberculosis hypothetical 43.3 kDa protein Rv0228 or MT0238 or MTCY08D5.23 TR:P96410 (EMBL:Z92669) (407 aa) fasta scores: E(): 1.2e-31, 38.84% id in 381 aa, and to Streptomyces thermotolerans macrolide antibiotics 3-O-acyltransferase AcyA TR:Q56074 (EMBL:D30759) (389 aa) fasta scores: E(): 6e-07, 30.43% id in 322 aa, and to Streptomyces mycarofaciens acyltransferase MdmB SW:MDMB_STRMY (Q00718) (387 aa) fasta scores: E(): 8e-07, 29.14% id in 398 aa. ORF overlaps with convergent downstream ORF.
 
   
 0.890
DIP0445
Putative membrane protein; Low similarity to Mycobacterium leprae putative integral membrane protein ML2581 TR:Q9CD18 (EMBL:AL583926) (427 aa) fasta scores: E(): 2.5, 24.7% id in 344 aa.
 
   
 0.842
DIP2098
Putative secreted protein; No significant database matches.
  
     0.755
DIP2179
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.5 kDa protein Rv0224c or MTCY08D5.19c TR:P96406 (EMBL:Z92669) (254 aa) fasta scores: E(): 2.9e-56, 63.41% id in 246 aa, and to Streptomyces coelicolor putative methyltransferase SCC53.08c TR:Q9KXK3 (EMBL:AL357591) (244 aa) fasta scores: E(): 7.1e-06, 32.94% id in 173 aa.
  
     0.753
DIP1447
Putative membrane protein; Low similarity to Mycobacterium tuberculosis CDC1551 hypothetical 19.3 kDa protein MT2802.1 TR:AAK47121 (EMBL:AE007108) (180 aa) fasta scores: E(): 3.3e-07, 25.68% id in 183 aa.
  
     0.752
DIP1556
Putative membrane protein; Low similarity to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT1645 TR:AAK45914 (EMBL:AE007029) (235 aa) fasta scores: E(): 1e-08, 28.64% id in 206 aa.
  
     0.748
DIP0793
Putative secreted protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2601 TR:AAK46909 (EMBL:AE007096) (240 aa) fasta scores: E(): 4.3e-31, 46.31% id in 244 aa. Note: Contains a putative twin-arginine translocation (TAT) system recognition motif (RRSFLT) at the N-terminal region.
  
     0.744
DIP1697
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 hypothetical 10.3 kDa protein MT2407 TR:AAK46700 (EMBL:AE007081) (97 aa) fasta scores: E(): 2.2e-05, 46.42% id in 56 aa.
  
     0.709
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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