STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2178Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 42.1 kDa protein Rv0225 or MTCY08D5.20 TR:P96407 (EMBL:Z92669) (384 aa) fasta scores: E(): 3.5e-62, 51.48% id in 371 aa. ORF overlaps with convergent downstream ORF. (384 aa)    
Predicted Functional Partners:
DIP2179
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 27.5 kDa protein Rv0224c or MTCY08D5.19c TR:P96406 (EMBL:Z92669) (254 aa) fasta scores: E(): 2.9e-56, 63.41% id in 246 aa, and to Streptomyces coelicolor putative methyltransferase SCC53.08c TR:Q9KXK3 (EMBL:AL357591) (244 aa) fasta scores: E(): 7.1e-06, 32.94% id in 173 aa.
 
     0.898
DIP2174
Similar to Mycobacterium leprae possible integral membrane protein ML2570 TR:Q9CD19 (EMBL:AL583926) (1405 aa) fasta scores: E(): 2.5e-17, 37.3% id in 823 aa, and to Mycobacterium tuberculosis hypothetical 146.3 kDa protein Rv0236c or MT0247 or MTV034.01c or MTV034.02c or MTCY08D5.32c TR:AAK44467 (EMBL:Z92669) (1400 aa) fasta scores: E(): 7.4e-17, 38.32% id in 822 aa. ORF overlaps with convergent downstream ORF.
 
   
 0.746
DIP2176
Similar to Mycobacterium leprae putative integral membrane protein Ml2581 TR:Q9CD18 (EMBL:AL583926) (427 aa) fasta scores: E(): 8.6e-14, 27.79% id in 367 aa.
  
     0.722
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
   
 0.701
DIP2177
Putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 59.1 kDa protein Rv0226c or MTCY08D5.21c TR:P96408 (EMBL:Z92669) (576 aa) fasta scores: E(): 6e-08, 30% id in 530 aa. ORF overlaps with convergent downstream ORF.
  
     0.692
DIP0361
Putative bifunctional protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.
  
  
 0.634
uvrD
Putative DNA helicase II; Similar to Mycobacterium tuberculosis probable DNA helicase II homolog UvrD or Rv3198c or MT3291 or MTV014.42c SW:UVRD_MYCTU (O53344) (700 aa) fasta scores: E(): 2.7e-133, 58.92% id in 689 aa, and to Escherichia coli DNA helicase II UvrD or MutU or PdeB or Rad or RecL or B3813 SW:UVRD_ECOLI (P03018) (720 aa) fasta scores: E(): 7.8e-37, 32.16% id in 656 aa.
    
 
 0.626
DIP1119
Similar to Mycobacterium leprae hypothetical protein ML0099 TR:Q9CDB3 (EMBL:AL583917) (336 aa) fasta scores: E(): 7e-07, 27.58% id in 261 aa, and to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv3802c or MTV026.07c TR:O53581 (EMBL:AL022076) (336 aa) fasta scores: E(): 4.2e-06, 27.98% id in 243 aa.
  
     0.573
DIP2191
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv3802c or MTV026.07c TR:O53581 (EMBL:AL022076) (336 aa) fasta scores: E(): 3.2e-34, 41.32% id in 317 aa.
  
   
 0.549
DIP1690
Putative membrane protein; Similar to Mycobacterium leprae hypothetical 50.2 kDa protein ML1338 or MLC1351.25 TR:O05686 (EMBL:Z95117) (440 aa) fasta scores: E(): 1.8e-11, 29.77% id in 393 aa.
  
     0.542
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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