Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trmBConserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (259 aa)    
Predicted Functional Partners:
DIP2182
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 26.2 kDa protein Rv0207c or MT0217 or MTCY08D5.02c TR:AAK44438 (EMBL:Z92669) (244 aa) fasta scores: E(): 8.6e-51, 64.03% id in 203 aa.
  
  
 0.950
DIP2185
Putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 12.6 kDa protein Rv0401 or MTCY04D9.14 TR:P95210 (EMBL:Z84725) (123 aa) fasta scores: E(): 5.3e-11, 36.6% id in 112 aa.
     
 0.825
DIP2184
Putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 44.0 kDa protein Rv0204c or MT0214 or MTV033.12c TR:O53655 (EMBL:AL021928) (412 aa) fasta scores: E(): 3.4e-15, 30.24% id in 324 aa.
     
 0.824
DIP2183
Similar to Mycobacterium tuberculosis putative membrane protein MmpL3 or Rv0206c or MT0216 or MTV033.14c or MTCY08D5.01c SW:MML3_MYCTU (O53657) (944 aa) fasta scores: E(): 2.1e-45, 44.69% id in 754 aa, and to Streptomyces coelicolor putative integral membrane protein SCC24.25 TR:Q9L092 (EMBL:AL163003) (743 aa) fasta scores: E(): 4.6e-42, 34.79% id in 750 aa.
  
  
 0.820
DIP1249
Conserved hypothetical protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
  
 0.789
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.693
DIP1321
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 48.5 kDa protein Rv1407 or MT1451 or MTCY21B4.24 SWALL:YE07_MYCTU (SWALL:P71675) (457 aa) fasta scores: E(): 6.2e-86, 55.4% id in 453 aa, and to Escherichia coli Sun protein Sun or Fmu or Fmv or RsmB or B3289 SWALL:SUN_ECOLI (SWALL:P36929) (429 aa) fasta scores: E(): 1.2e-31, 33.63% id in 449 aa; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.621
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.563
tilS
Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
   
  
 0.496
rpmD
Similar to Streptomyces coelicolor 50S ribosomal protein L30 RpmD or SCD31.45 SW:RL30_STRCO (P46789) (60 aa) fasta scores: E(): 2.1e-08, 53.57% id in 56 aa.
   
    0.494
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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