Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DIP2183Similar to Mycobacterium tuberculosis putative membrane protein MmpL3 or Rv0206c or MT0216 or MTV033.14c or MTCY08D5.01c SW:MML3_MYCTU (O53657) (944 aa) fasta scores: E(): 2.1e-45, 44.69% id in 754 aa, and to Streptomyces coelicolor putative integral membrane protein SCC24.25 TR:Q9L092 (EMBL:AL163003) (743 aa) fasta scores: E(): 4.6e-42, 34.79% id in 750 aa. (746 aa)    
Predicted Functional Partners:
DIP2184
Putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 44.0 kDa protein Rv0204c or MT0214 or MTV033.12c TR:O53655 (EMBL:AL021928) (412 aa) fasta scores: E(): 3.4e-15, 30.24% id in 324 aa.
 
   
 0.874
DIP2182
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 26.2 kDa protein Rv0207c or MT0217 or MTCY08D5.02c TR:AAK44438 (EMBL:Z92669) (244 aa) fasta scores: E(): 8.6e-51, 64.03% id in 203 aa.
 
  
 0.846
DIP2185
Putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 12.6 kDa protein Rv0401 or MTCY04D9.14 TR:P95210 (EMBL:Z84725) (123 aa) fasta scores: E(): 5.3e-11, 36.6% id in 112 aa.
     
 0.843
trmB
Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.820
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
  
 
 
 0.601
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
   
 
 0.510
DIP0715
Similar to Mycobacterium leprae putative membrane protein ML0806 TR:Q9CCH6 (EMBL:AL583919) (173 aa) fasta scores: E(): 2e-07, 38.34% id in 133 aa.
  
     0.438
DIP0793
Putative secreted protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2601 TR:AAK46909 (EMBL:AE007096) (240 aa) fasta scores: E(): 4.3e-31, 46.31% id in 244 aa. Note: Contains a putative twin-arginine translocation (TAT) system recognition motif (RRSFLT) at the N-terminal region.
  
     0.438
DIP0106
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 8.6 kDa protein Rv1590 or MT1625 or MTCY336.14c TR:O06600 (EMBL:Z95586) (79 aa) fasta scores: E(): 4.1e-11, 67.24% id in 58 aa.
  
     0.424
qcrB
Ubiquinol-cytochrome C reductase cytochrome B subunit; Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
  
   
 0.417
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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