STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2192Putative exported protein; N-terminal region presents very low similarity to the following: Corynebacterium equii virulence associated protein VapA TR:Q9EUL9 (EMBL:AF116907) (189 aa) fasta scores: E(): 0.7, 27.92% id in 111 aa, and to Staphylococcus aureus hypothetical protein SAV2001 TR:BAB58163 (EMBL:AP003364) (154 aa) fasta scores: E(): 0.99, 26.61% id in 124 aa, and to Corynebacterium equii virulence-associated 15-17-kDa antigen VapA TR:Q57470 (EMBL:D21236) (189 aa) fasta scores: E(): 4.1, 27.02% id in 111 aa. (171 aa)    
Predicted Functional Partners:
DIP2191
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv3802c or MTV026.07c TR:O53581 (EMBL:AL022076) (336 aa) fasta scores: E(): 3.2e-34, 41.32% id in 317 aa.
     
 0.876
csp1
Putative secreted antigen; Similar to Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 1.8e-147, 57.51% id in 659 aa, and similar to but longer than Mycobacterium intracellulare antigen 85-B precursor FbpB SW:A85B_MYCIT (Q49575) (330 aa) fasta scores: E(): 1.8e-29, 37.18% id in 320 aa.
     
 0.875
DIP2190
Similar to Mycobacterium tuberculosis putative polyketide synthase FadD32 or Rv3801c or MT3908 or MTV026.06c TR:O53580 (EMBL:AL022076) (637 aa) fasta scores: E(): 6.4e-78, 41.07% id in 616 aa, and to Myxococcus xanthus saframycin MX1 synthetase B SafB TR:Q50857 (EMBL:U24657) (1770 aa) fasta scores: E(): 7.7e-59, 37.52% id in 557 aa.
       0.711
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
     
 0.610
DIP2194
Putative secreted antigen; Similar to Mycobacterium avium antigen 85-C precursor FbpC SW:A85C_MYCAV (O52972) (352 aa) fasta scores: E(): 3.7e-29, 34.32% id in 335 aa, and similar to but shorter than Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 1.5e-28, 35.69% id in 297 aa.
       0.565
DIP2195
Similar to Mycobacterium tuberculosis putative membrane protein Rv3805c or MT3912 or MTV026.10c TR:O53582 (EMBL:AL022076) (627 aa) fasta scores: E(): 4.1e-25, 36.36% id in 594 aa.
       0.515
DIP2196
Conserved putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 32.7 kDa protein Rv3806c or MTV026.11c TR:O53583 (EMBL:AL022076) (302 aa) fasta scores: E(): 1e-67, 59.6% id in 302 aa, and to Streptomyces coelicolor putative integral membrane protein SC5G8.12 TR:Q9KZA2 (EMBL:AL353872) (322 aa) fasta scores: E(): 1.7e-49, 44.51% id in 310 aa; Belongs to the UbiA prenyltransferase family.
     
 0.515
DIP2198
Conserved hypothetical protein; Similar proteins from other actinomycetes eg. Mycobacterium tuberculosis hypothetical 71.5 kDa protein Rv3808c or MT3915 or MTV026.13c TR:O53585 (EMBL:AL022076) (637 aa) fasta scores: E(): 6.3e-88, 54.79% id in 657 aa.
       0.515
pccB
Putative sortase-substrate protein (pseudogene); 1 probable transmembrane helix predicted for DIP2187 by TMHMM2.0.
       0.451
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (44%) [HD]