Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
csp1Putative secreted antigen; Similar to Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 1.8e-147, 57.51% id in 659 aa, and similar to but longer than Mycobacterium intracellulare antigen 85-B precursor FbpB SW:A85B_MYCIT (Q49575) (330 aa) fasta scores: E(): 1.8e-29, 37.18% id in 320 aa. (638 aa)    
Predicted Functional Partners:
DIP2191
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv3802c or MTV026.07c TR:O53581 (EMBL:AL022076) (336 aa) fasta scores: E(): 3.2e-34, 41.32% id in 317 aa.
 
  
 0.975
DIP2192
Putative exported protein; N-terminal region presents very low similarity to the following: Corynebacterium equii virulence associated protein VapA TR:Q9EUL9 (EMBL:AF116907) (189 aa) fasta scores: E(): 0.7, 27.92% id in 111 aa, and to Staphylococcus aureus hypothetical protein SAV2001 TR:BAB58163 (EMBL:AP003364) (154 aa) fasta scores: E(): 0.99, 26.61% id in 124 aa, and to Corynebacterium equii virulence-associated 15-17-kDa antigen VapA TR:Q57470 (EMBL:D21236) (189 aa) fasta scores: E(): 4.1, 27.02% id in 111 aa.
     
 0.876
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
 
  
 0.875
DIP2190
Similar to Mycobacterium tuberculosis putative polyketide synthase FadD32 or Rv3801c or MT3908 or MTV026.06c TR:O53580 (EMBL:AL022076) (637 aa) fasta scores: E(): 6.4e-78, 41.07% id in 616 aa, and to Myxococcus xanthus saframycin MX1 synthetase B SafB TR:Q50857 (EMBL:U24657) (1770 aa) fasta scores: E(): 7.7e-59, 37.52% id in 557 aa.
 
 
 
 0.833
DIP2195
Similar to Mycobacterium tuberculosis putative membrane protein Rv3805c or MT3912 or MTV026.10c TR:O53582 (EMBL:AL022076) (627 aa) fasta scores: E(): 4.1e-25, 36.36% id in 594 aa.
 
     0.783
DIP2194
Putative secreted antigen; Similar to Mycobacterium avium antigen 85-C precursor FbpC SW:A85C_MYCAV (O52972) (352 aa) fasta scores: E(): 3.7e-29, 34.32% id in 335 aa, and similar to but shorter than Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 1.5e-28, 35.69% id in 297 aa.
 
   
0.709
DIP1119
Similar to Mycobacterium leprae hypothetical protein ML0099 TR:Q9CDB3 (EMBL:AL583917) (336 aa) fasta scores: E(): 7e-07, 27.58% id in 261 aa, and to Mycobacterium tuberculosis hypothetical 35.4 kDa protein Rv3802c or MTV026.07c TR:O53581 (EMBL:AL022076) (336 aa) fasta scores: E(): 4.2e-06, 27.98% id in 243 aa.
 
  
 0.684
DIP2049
Low similarity to Streptomyces coelicolor putative ABC transporter integral membrane protein SCE8.16c SWALL:Q9Z4W1 (EMBL:AL035654) (264 aa) fasta scores: E(): 1.7e-09, 26.37% id in 254 aa.
  
     0.659
DIP1690
Putative membrane protein; Similar to Mycobacterium leprae hypothetical 50.2 kDa protein ML1338 or MLC1351.25 TR:O05686 (EMBL:Z95117) (440 aa) fasta scores: E(): 1.8e-11, 29.77% id in 393 aa.
  
     0.657
DIP1556
Putative membrane protein; Low similarity to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT1645 TR:AAK45914 (EMBL:AE007029) (235 aa) fasta scores: E(): 1e-08, 28.64% id in 206 aa.
  
     0.641
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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