Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP2196Conserved putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 32.7 kDa protein Rv3806c or MTV026.11c TR:O53583 (EMBL:AL022076) (302 aa) fasta scores: E(): 1e-67, 59.6% id in 302 aa, and to Streptomyces coelicolor putative integral membrane protein SC5G8.12 TR:Q9KZA2 (EMBL:AL353872) (322 aa) fasta scores: E(): 1.7e-49, 44.51% id in 310 aa; Belongs to the UbiA prenyltransferase family. (325 aa)    
Predicted Functional Partners:
DIP2195
Similar to Mycobacterium tuberculosis putative membrane protein Rv3805c or MT3912 or MTV026.10c TR:O53582 (EMBL:AL022076) (627 aa) fasta scores: E(): 4.1e-25, 36.36% id in 594 aa.
 
  
 0.973
DIP2198
Conserved hypothetical protein; Similar proteins from other actinomycetes eg. Mycobacterium tuberculosis hypothetical 71.5 kDa protein Rv3808c or MT3915 or MTV026.13c TR:O53585 (EMBL:AL022076) (637 aa) fasta scores: E(): 6.3e-88, 54.79% id in 657 aa.
  
  
 0.924
DIP0162
Putative oxidoreductase, FAD-binding; Similar to Mycobacterium tuberculosis CDC1551 oxidoreductase, FAD-binding MT3898 TR:AAK48263 (EMBL:AE007183) (463 aa) fasta scores: E(): 4.2e-118, 67.57% id in 478 aa.
 
  
 0.915
DIP2197
Putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 17.2 kDa protein Rv3807c or MTV026.12 TR:O53584 (EMBL:AL022076) (165 aa) fasta scores: E(): 7.9e-29, 52.56% id in 156 aa, and to Streptomyces coelicolor putative integral membrane protein SC5G8.11 TR:Q9KZA3 (EMBL:AL353872) (169 aa) fasta scores: E(): 9.1e-17, 46.04% id in 139 aa.
 
  
 0.860
DIP0161
Similar to Mycobacterium leprae putative oxidoreductase ML0108 TR:Q9CDA5 (EMBL:AL583917) (254 aa) fasta scores: E(): 5.6e-50, 57.14% id in 252 aa.
 
  
 0.787
DIP1237
Similar to Mycobacterium tuberculosis putative oxidoreductase Rv2073c or MT2133 or MTCY49.12c SWALL:YK73_MYCTU (SWALL:Q10681) (249 aa) fasta scores: E(): 1.3e-38, 46.82% id in 252 aa, and to Streptomyces coelicolor putative short-chain dehydrogenase SC5G8.09c SWALL:Q9KZA5 (EMBL:AL353872) (256 aa) fasta scores: E(): 3.1e-27, 37.94% id in 253 aa.
 
    0.787
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
    0.748
DIP0166
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 13.4 kDa protein Rv3789 or MT3897 or MTCY13D12.23 SW:Y1I9_MYCTU (P72055) (121 aa) fasta scores: E(): 4.2e-17, 48.78% id in 123 aa.
 
     0.724
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
     
 0.652
DIP2194
Putative secreted antigen; Similar to Mycobacterium avium antigen 85-C precursor FbpC SW:A85C_MYCAV (O52972) (352 aa) fasta scores: E(): 3.7e-29, 34.32% id in 335 aa, and similar to but shorter than Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 1.5e-28, 35.69% id in 297 aa.
       0.629
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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