STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2197Putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 17.2 kDa protein Rv3807c or MTV026.12 TR:O53584 (EMBL:AL022076) (165 aa) fasta scores: E(): 7.9e-29, 52.56% id in 156 aa, and to Streptomyces coelicolor putative integral membrane protein SC5G8.11 TR:Q9KZA3 (EMBL:AL353872) (169 aa) fasta scores: E(): 9.1e-17, 46.04% id in 139 aa. (164 aa)    
Predicted Functional Partners:
DIP2196
Conserved putative integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 32.7 kDa protein Rv3806c or MTV026.11c TR:O53583 (EMBL:AL022076) (302 aa) fasta scores: E(): 1e-67, 59.6% id in 302 aa, and to Streptomyces coelicolor putative integral membrane protein SC5G8.12 TR:Q9KZA2 (EMBL:AL353872) (322 aa) fasta scores: E(): 1.7e-49, 44.51% id in 310 aa; Belongs to the UbiA prenyltransferase family.
 
  
 0.863
DIP2195
Similar to Mycobacterium tuberculosis putative membrane protein Rv3805c or MT3912 or MTV026.10c TR:O53582 (EMBL:AL022076) (627 aa) fasta scores: E(): 4.1e-25, 36.36% id in 594 aa.
 
    0.857
DIP2198
Conserved hypothetical protein; Similar proteins from other actinomycetes eg. Mycobacterium tuberculosis hypothetical 71.5 kDa protein Rv3808c or MT3915 or MTV026.13c TR:O53585 (EMBL:AL022076) (637 aa) fasta scores: E(): 6.3e-88, 54.79% id in 657 aa.
       0.780
DIP2199
Putative conserved integral membrane protein; Similar to Corynebacterium ammoniagenes Orf2 protein TR:Q9RHY7 (EMBL:AB003155) (163 aa) fasta scores: E(): 6.5e-14, 39.21% id in 153 aa, and to Escherichia coli hypothetical protein YbjG or B0841 SW:YBJG_ECOLI (P75806) (198 aa) fasta scores: E(): 1.9e-06, 32.69% id in 156 aa.
 
     0.719
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.534
DIP2182
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 26.2 kDa protein Rv0207c or MT0217 or MTCY08D5.02c TR:AAK44438 (EMBL:Z92669) (244 aa) fasta scores: E(): 8.6e-51, 64.03% id in 203 aa.
  
     0.532
DIP2190
Similar to Mycobacterium tuberculosis putative polyketide synthase FadD32 or Rv3801c or MT3908 or MTV026.06c TR:O53580 (EMBL:AL022076) (637 aa) fasta scores: E(): 6.4e-78, 41.07% id in 616 aa, and to Myxococcus xanthus saframycin MX1 synthetase B SafB TR:Q50857 (EMBL:U24657) (1770 aa) fasta scores: E(): 7.7e-59, 37.52% id in 557 aa.
   
  0.528
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
     
 0.492
DIP2194
Putative secreted antigen; Similar to Mycobacterium avium antigen 85-C precursor FbpC SW:A85C_MYCAV (O52972) (352 aa) fasta scores: E(): 3.7e-29, 34.32% id in 335 aa, and similar to but shorter than Corynebacterium glutamicum PS1 protein precursor Csp1 SW:CSP1_CORGL (Q01377) (657 aa) fasta scores: E(): 1.5e-28, 35.69% id in 297 aa.
       0.468
gbsA
Similar to Bacillus subtilis betaine aldehyde dehydrogenase GbsA SW:DHAB_BACSU (P71016) (490 aa) fasta scores: E(): 2e-73, 54.63% id in 496 aa, and to Streptomyces coelicolor betaine aldehyde dehydrogenase GbsA TR:Q9K3J2 (EMBL:AL389898) (509 aa) fasta scores: E(): 3.2e-88, 55.75% id in 504 aa.
       0.466
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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