STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
betTSimilar to Escherichia coli high-affinity choline transport protein BetT or B0314 or Z0401 or ECS0360 SW:BETT_ECOLI (P17447) (677 aa) fasta scores: E(): 1.9e-118, 53.14% id in 668 aa, and to Erwinia amylovora high-affinity choline transport protein BetT TR:Q9F806 (EMBL:AF264948) (676 aa) fasta scores: E(): 2.5e-116, 51.98% id in 681 aa; Belongs to the BCCT transporter (TC 2.A.15) family. (741 aa)    
Predicted Functional Partners:
greA
Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
      
 0.617
gbsA
Similar to Bacillus subtilis betaine aldehyde dehydrogenase GbsA SW:DHAB_BACSU (P71016) (490 aa) fasta scores: E(): 2e-73, 54.63% id in 496 aa, and to Streptomyces coelicolor betaine aldehyde dehydrogenase GbsA TR:Q9K3J2 (EMBL:AL389898) (509 aa) fasta scores: E(): 3.2e-88, 55.75% id in 504 aa.
  
  
 0.609
DIP2199
Putative conserved integral membrane protein; Similar to Corynebacterium ammoniagenes Orf2 protein TR:Q9RHY7 (EMBL:AB003155) (163 aa) fasta scores: E(): 6.5e-14, 39.21% id in 153 aa, and to Escherichia coli hypothetical protein YbjG or B0841 SW:YBJG_ECOLI (P75806) (198 aa) fasta scores: E(): 1.9e-06, 32.69% id in 156 aa.
       0.492
betA
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
  
  
 0.474
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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