STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2207Conserved putative secreted protein; Similar to Mycobacterium tuberculosis Csp or Rv3811 or MT3918 or MTV026.16 TR:O86334 (EMBL:Z97188) (539 aa) fasta scores: E(): 6.2e-33, 41.84% id in 411 aa, and to Streptomyces coelicolor putative secreted protein SCE34.21c TR:Q9KZK5 (EMBL:AL353862) (416 aa) fasta scores: E(): 5.6e-20, 28.74% id in 421 aa. Contains a proline/alanine rich region at residues 398-44, no present in homologues. (606 aa)    
Predicted Functional Partners:
DIP0264
Putative helicase; Similar to Mycobacterium tuberculosis CDC1551 DNA polymerase III, epsilon subunit MT3814 TR:AAK48182 (EMBL:AE007178) (329 aa) fasta scores: E(): 1.3e-07, 25.37% id in 335 aa, and to Bacillus subtilis probable ATP-dependent helicase DinG homolog SW:DING_BACSU (P54394) (931 aa) fasta scores: E(): 0.48, 24.07% id in 108 aa.
  
     0.490
DIP2182
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 26.2 kDa protein Rv0207c or MT0217 or MTCY08D5.02c TR:AAK44438 (EMBL:Z92669) (244 aa) fasta scores: E(): 8.6e-51, 64.03% id in 203 aa.
  
     0.488
DIP1447
Putative membrane protein; Low similarity to Mycobacterium tuberculosis CDC1551 hypothetical 19.3 kDa protein MT2802.1 TR:AAK47121 (EMBL:AE007108) (180 aa) fasta scores: E(): 3.3e-07, 25.68% id in 183 aa.
  
     0.460
DIP1357
Hypothetical protein; No significant database matches.
  
     0.455
DIP0392
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 32.9 kDa protein Rv0495c or MT0515 or MTCY20G9.21c SW:Y495_MYCTU (Q11160) (296 aa) fasta scores: E(): 3.6e-25, 44.07% id in 270 aa.
  
     0.443
DIP1157
Conserved hypothetical protein; N-terminal region similar to Streptomyces coelicolor hypothetical 18.8 kDa protein SC9H11.26c SWALL:Q9KYL5 (EMBL:AL356592) (177 aa) fasta scores: E(): 9.8e-11, 35.13% id in 148 aa. Note: Possible colied-coil region at C-terminal domain from residue 242 till the end.
  
     0.439
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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