STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2212Similar to Escherichia coli hypothetical 22.3 kDa protein in iap-cysH intergenic region YgcH or B2756 SW:YGCH_ECOLI (Q46897) (199 aa) fasta scores: E(): 0.042, 24.873% id in 197 aa. (228 aa)    
Predicted Functional Partners:
DIP2213
Putative helicase; Similar to Escherichia coli hypothetical 100.5 kDa protein in iap-cysH intergenic region YgcB or B2761 SW:YGCB_ECOLI (P38036) (888 aa) fasta scores: E(): 1.1e-28, 28.827% id in 784 aa.
 
 
 
 0.999
DIP2209
Conserved hypothetical protein; Similar to Escherichia coli O157:H7 hypothetical 38.4 kDa protein ECS3612 TR:BAB37035 (EMBL:AP002562) (351 aa) fasta scores: E(): 8.7e-11, 33.333% id in 306 aa.
 
 
 0.996
DIP2208
Similar to Escherichia coli hypothetical protein YgcI precursor or B2757 SW:YGCI_ECOLI (Q46898) (224 aa) fasta scores: E(): 0.02, 26.816% id in 179 aa.
 
 
 0.989
cas1-2
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.970
DIP2215
Similar to Escherichia coli hypothetical 10.5 kDa protein in iap-cysH intergenic region YgbF or B2754 SW:YGBF_ECOLI (P45956) (94 aa) fasta scores: E(): 0.0075, 26.667% id in 90 aa.
 
  
 0.965
DIP2211
Hypothetical protein; No significant database matches.
   
 
 0.908
DIP1894
Hypothetical protein; No significant database matches to the full length CDS. Internal region is weakly similar to an internal region of Thermoplasma volcanium hypothetical protein TVG1552703 TR:BAB60643 (EMBL:AP000996) (974 aa) fasta scores: E(): 5.5e-05, 21.86% id in 773 aa.
  
     0.657
DIP0804
Hypothetical protein; No significant database matches.
  
     0.607
DIP1895
Putative DNA methylase; Internal region is similar to an internal regions of Salmonella typhimurium type III restriction-modification system StyLTI enzyme Mod SW:T3MO_SALTY (P40814) (651 aa) fasta scores: E(): 1.8e-20, 29.39% id in 398 aa, and Xylella fastidiosa methyltransferase XF1968 TR:Q9PC17 (EMBL:AE004016) (534 aa) fasta scores: E(): 5.9e-33, 35.25% id in 417 aa.
  
     0.507
DIP0805
Putative DNA methylase; Similar to Haemophilus influenzae putative type III restriction-modification system HinDVIp enzyme Mod HI1056 SW:T3MH_HAEIN (P71366) (629 aa) fasta scores: E(): 8.3e-26, 29.960% id in 504 aa, and to Lactococcus lactis modification methylase LlaFI Mod TR:Q9Z6H7 (EMBL:AF054600) (680 aa) fasta scores: E(): 5.8e-13, 29.369% id in 412 aa.
  
     0.470
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.