STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ssb2Similar to Mycobacterium tuberculosis single-strand binding protein Ssb or Rv0054 or MT0060 or MTCY21D4.17 SW:SSB_MYCTU (P71711) (164 aa) fasta scores: E(): 7.2e-31, 56.647% id in 173 aa, and to Bacillus subtilis single-strand binding protein Ssb SW:SSB_BACSU (P37455) (172 aa) fasta scores: E(): 3.4e-13, 38.372% id in 172 aa. Note: Also similar to DIP2290 (193 aa) fasta scores: E(): 6.4e-45, 68.750% identity in 176 aa overlap. (171 aa)    
Predicted Functional Partners:
DIP1804
Similar to Mycobacterium tuberculosis single-strand binding protein Ssb SW:SSB_MYCTU (P71711) (164 aa) fasta scores: E(): 0.00073, 29.11% id in 158 aa, and to Mycobacterium smegmatis single-stranded DNA-binding protein TR:Q9AFI5 (EMBL:AF349434) (165 aa) fasta scores: E(): 0.00024, 27.95% id in 161 aa.
  
  
 
0.907
ssb1
Similar to Mycobacterium tuberculosis single-strand binding protein Ssb or Rv0054 or MT0060 or MTCY21D4.17 SWALL:SSB_MYCTU (SWALL:P71711) (164 aa) fasta scores: E(): 2e-27, 60.2% id in 191 aa. Note: Also similar to DIP2216 (171 aa) fasta scores: E(): 2.6e-44, 68.750% identity in 176 aa overlap.
  
  
 
0.902
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
 
  
 0.803
DIP2217
Putative DNA-binding protein; No significant database matches.
       0.718
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 
 0.688
priA
Putative primosomal protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
    
 
 0.660
dnaE
Similar to Streptomyces coelicolor DNA polymerase III alpha subunit DnaE or SC4G6.33c SW:DP3A_STRCO (Q9Z618) (1179 aa) fasta scores: E(): 0, 53.84% id in 1185 aa, and to Escherichia coli DNA polymerase III alpha subunit DnaE or PolC or B0184 SW:DP3A_ECOLI (P10443) (1160 aa) fasta scores: E(): 6.2e-94, 35.39% id in 1198 aa.
  
 
 
 0.657
DIP1678
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 39.8 kDa protein ML1637 or MLCB1243.38 TR:O69483 (EMBL:AL023635) (371 aa) fasta scores: E(): 1.8e-73, 54.61% id in 379 aa.
   
 
 0.653
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
    0.628
rplJ
50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
    0.611
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.