STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2226Similar to Actinomyces naeslundii fimbrial subunit type 2 precursor SW:FM2_ACTNA (P12616) (534 aa) fasta scores: E(): 1e-30, 38.276% id in 580 aa, and to Actinomyces viscosus fimbrial subunit type 1 precursor SW:FM1_ACTVI (P18477) (533 aa) fasta scores: E(): 7.4e-12, 29.856% id in 556 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain. (555 aa)    
Predicted Functional Partners:
DIP2225
Similar to Actinomyces naeslundii putative fimbria-associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 3.2e-52, 51.254% id in 279 aa, and to Bifidobacterium longum NCC2705 sortase-like protein BL0676 SWALL:AAN24497 (EMBL:AE014690) (328 aa) fasta scores: E(): 3.6e-28, 34.02% id in 291 aa, and to Staphylococcus aureus subsp aureus Mu50 sortase SrtA TR:BAB58690 (EMBL:AP003365) (206 aa) fasta scores: E(): 0.027, 29.371% id in 143 aa.
 
   
 0.879
DIP2227
Probable surface-anchored fimbrial subunit; Similar to Actinomyces naeslundii hypothetical 103.4 kDa protein TR:Q9EV17 (EMBL:AJ401093) (976 aa) fasta scores: E(): 0.0003, 29.146% id in 597 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain.
 
     0.874
DIP2224
Similar to Actinomyces naeslundii putative fimbriae-associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 2.3e-33, 42.500% id in 280 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 0.0034, 26.115% id in 157 aa.
 
     0.872
DIP0233
Similar to Actinomyces naeslundii putative fimbrial associated protein TR:O05996 (EMBL:U85709) (280 aa) fasta scores: E(): 4.5e-16, 40.000% id in 215 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 1.2, 26.923% id in 156 aa. Note: Also similar to DIP0236 (312 aa) E(): 5.7e-25; 45.342% identity in 322 aa overlap, DIP2224, DIP2012 and DIP2225.
 
     0.778
DIP0236
Similar to Actinomyces naeslundii putative fimbrial associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 1.2e-31, 42.802% id in 257 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 0.094, 27.559% id in 127 aa. Note: Also similar to DIP0233 (329 aa) E(): 5.2e-25; 45.031% identity in 322 aa overlap. Note: Also similar to DIP2012, DIP2224 and DIP2225.
 
     0.778
DIP2012
Putative fimbrial associated sortase-like protein; Similar to Actinomyces viscosus sortase-like protein SWALL:Q9AJ92 (EMBL:AF106034) (387 aa) fasta scores: E(): 2.7e-39, 43.47% id in 276 aa, and to Bifidobacterium longum NCC2705 sortase-like protein BL0676 SWALL:AAN24497 (EMBL:AE014690) (328 aa) fasta scores: E(): 3.7e-28, 36.94% id in 268 aa, and to Streptococcus pneumoniae sortase, putative SP0466 SWALL:AAK74626 (EMBL:AE007358) (279 aa) fasta scores: E(): 3e-21, 31.78% id in 258 aa.
 
     0.777
pyk
Pyruvate kinase; Similar to Corynebacterium glutamicum pyruvate kinase Pyk SW:KPYK_CORGL (Q46078) (475 aa) fasta scores: E(): 1.3e-146, 83.36% id in 469 aa, and to Bacillus psychrophilus pyruvate kinase Pyk SW:KPYK_BACPY (P51182) (586 aa) fasta scores: E(): 6.9e-64, 41.45% id in 480 aa.
   
    0.420
DIP2310
Conserved hypothetical protein; Similar to N-terminal half of Pyrococcus abyssi hypothetical 48.8 kDa protein Pab1002 SWALL:Q9UYK0 (EMBL:AJ248287) (428 aa) fasta scores: E(): 0.081, 30.05% id in 193 aa.
  
     0.408
DIP2062
Putative surface anchored protein; Low similarity to Streptococcus agalactiae BPS protein precursor Sar5 TR:Q9XAS7 (EMBL:AJ133114) (979 aa) fasta scores: E(): 7.1e-12, 32.35% id in 442 aa, and to Staphylococcus epidermidis putative cell-surface adhesin SdrF TR:Q9KI14 (EMBL:AF245041) (1733 aa) fasta scores: E(): 0.015, 24.86% id in 539 aa. Note: Contains a potential sortase anchor site (LAATG) upstream of the C-terminal region transmembrane domain.
  
     0.405
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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