STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpDSimilar to Mycobacterium leprae glycerol-3-phosphate dehydrogenase GlpD or ML0713 or L308_C1_179 SW:GLPD_MYCLE (P53435) (585 aa) fasta scores: E(): 5.7e-116, 55.35% id in 560 aa, and to Escherichia coli aerobic glycerol-3-phosphate dehydrogenase GlpD or GlyD or B3426 SW:GLPD_ECOLI (P13035) (501 aa) fasta scores: E(): 2.4e-38, 33.67% id in 493 aa. (577 aa)    
Predicted Functional Partners:
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 0.999
glpF
Similar to Bacillus subtilis glycerol uptake facilitator protein GlpF SW:GLPF_BACSU (P18156) (274 aa) fasta scores: E(): 2.1e-23, 45.83% id in 240 aa; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 0.982
gpsA
Similar to Mycobacterium tuberculosis glycerol-3-phosphate dehydrogenase GpsA or GpdA2 or Rv2982c or MT3060 or MTCY349.05 SWALL:GPDA_MYCTU (SWALL:P95113) (334 aa) fasta scores: E(): 8.7e-69, 59.27% id in 329 aa, and to Bacillus subtilis glycerol-3-phosphate dehydrogenase GpsA or GlyC SWALL:GPDA_BACSU (SWALL:P46919) (345 aa) fasta scores: E(): 2.1e-43, 40.78% id in 331 aa; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 0.930
DIP2336
Similar to but longer than a family of hypothetical proteins eg. Deinococcus radiodurans conserved hypothetical protein DRB0052 SWALL:Q9RZR3 (EMBL:AE001826) (133 aa) fasta scores: E(): 8.8e-10, 43.75% id in 128 aa, and to Staphylococcus aureus (strain N315) hypothetical protein SA0607 or SAV0652 SWALL:Q99VW9 (EMBL:AP003131) (120 aa) fasta scores: E(): 1.3e-09, 42.73% id in 117 aa.
    
 0.876
DIP2334
Putative dihydroxyacetone kinase sununit; Similar to Streptomyces coelicolor hypothetical 34.3 kDa protein SC4G1.39c SWALL:Q9FC11 (EMBL:AL391039) (330 aa) fasta scores: E(): 3e-61, 56.62% id in 332 aa, and to Selenomonas ruminantium subspruminantium dihydroxyacetone kinase Dhak1 SWALL:AAK84068 (EMBL:AF297121) (329 aa) fasta scores: E(): 7.8e-61, 56.19% id in 331 aa, and to Lycopersicon esculentum putative 3,4-dihydroxy-2-butanone kinase DhbK SWALL:DHBK_LYCES (SWALL:O04059) (594 aa) fasta scores: E(): 2.6e-42, 45.64% id in 333 aa. Lies upstream of a Dhak2 homologue.
    
 0.820
DIP2335
Similar to Selenomonas ruminantium subspruminantium dihydroxyacetone kinase Dhak2 SWALL:AAG14892 (EMBL:AF297121) (207 aa) fasta scores: E(): 6.6e-25, 48.51% id in 202 aa, and to Escherichia coli protein YcgS or B1199 SWALL:YCGS_ECOLI (SWALL:P76014) (210 aa) fasta scores: E(): 2e-22, 43.12% id in 211 aa. Lies downstream of a Dhak1 homologue.
    
 0.820
DIP1618
Putative acyltransferase; Similar to Corynebacterium glutamicum hypothetical 27.1 kDa protein TR:Q9KKE6 (EMBL:AF096280) (245 aa) fasta scores: E(): 1.9e-67, 67.91% id in 240 aa, and to Streptomyces coelicolor putative acyltransferase 2SCG1.03 TR:Q9FCD9 (EMBL:AL391014) (240 aa) fasta scores: E(): 1.3e-37, 46.63% id in 238 aa.
  
 
 0.817
lpdA
Similar to Mycobacterium tuberculosis dihydrolipoamide dehydrogenase LpdA or Rv3303c or MTV016.02c TR:O53355 (EMBL:AL021841) (493 aa) fasta scores: E(): 5.8e-110, 64.04% id in 470 aa, and to Bacillus subtilis dihydrolipoamide dehydrogenase PdhD or AceD or CitL SW:DLD1_BACSU (P21880) (470 aa) fasta scores: E(): 1.2e-36, 31.47% id in 467 aa.
  
  
 0.706
DIP2254
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 29.9 kDa protein GlpQ1 or Rv3842c or MT3950 or MTCY01A6.27 TR:P96236 (EMBL:Z83864) (274 aa) fasta scores: E(): 1e-08, 36.84% id in 247 aa, and to Streptomyces coelicolor putative phosphodiesterase 2SCG4.06 TR:Q9K3Q8 (EMBL:AL360034) (227 aa) fasta scores: E(): 1.2e-08, 28.5% id in 228 aa.
  
 0.677
odhA
2-oxoglutarate dehydrogenase, E1 and E2 components; Similar to Corynebacterium glutamicum 2-oxoglutarate dehydrogenase OdhA TR:P96746 (EMBL:D84102) (1257 aa) fasta scores: E(): 0, 77.37% id in 1242 aa, and to Mycobacterium leprae 2-oxoglutarate dehydrogenase, E1 and E2 components OdhA or ML1095 TR:Q9CC97 (EMBL:AL583920) (1260 aa) fasta scores: E(): 0, 59.37% id in 1253 aa. Similar in the N-terminus to Escherichia coli dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2) SucB or B0727 or Z0881 or ECS0752 SW:ODO2_ECOLI (P07016) blastp scores: E(): 4 [...]
  
 
 0.671
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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