STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP2239Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 28.5 kDa protein Rv3813c or MTCY409.17 TR:O07810 (EMBL:Z97188) (273 aa) fasta scores: E(): 4.2e-35, 41.69% id in 271 aa, and to Streptomyces coelicolor hypothetical 32.5 kDa protein SCD78.17c TR:Q9ZBY2 (EMBL:AL034355) (305 aa) fasta scores: E(): 2.3e-19, 34.29% id in 277 aa. (275 aa)    
Predicted Functional Partners:
DIP2238
Putative acyltransferase; Similar to Mycobacterium tuberculosis acyltransferase Rv3816c or MTCY409.14 TR:O07807 (EMBL:Z97188) (259 aa) fasta scores: E(): 2.5e-34, 47.6% id in 250 aa, and to Brassica napus lysophosphatidic acid acyltransferase Act2 TR:Q9LLY4 (EMBL:AF111161) (344 aa) fasta scores: E(): 4.3e-06, 29.05% id in 148 aa.
       0.826
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
  
    0.780
DIP2241
Similar to Streptomyces coelicolor putative GntR-family transcriptional regulator SC7E4.28c TR:Q9K492 (EMBL:AL359214) (254 aa) fasta scores: E(): 7.3e-21, 34.82% id in 224 aa, and to Escherichia coli fatty acyl responsive regulator FarR or G30 or B0730 SW:FARR_ECOLI (P13669) (240 aa) fasta scores: E(): 6.4e-14, 30.93% id in 236 aa.
       0.654
DIP2242
Conserved hypothetical protein; Similar to, but shorter than, Mycobacterium tuberculosis hypothetical 47.0 kDa protein Rv3835 or MTCY01A6.34c TR:P96243 (EMBL:Z83864) (449 aa) fasta scores: E(): 6.4e-31, 34.83% id in 310 aa.
       0.647
DIP2243
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.0 kDa protein Rv3836 or MTCY01A6.33c TR:P96242 (EMBL:Z83864) (137 aa) fasta scores: E(): 2.5e-18, 47.78% id in 113 aa, and to Streptomyces coelicolor hypothetical 13.1 kDa protein SCD25.30 TR:Q9RKJ2 (EMBL:AL118514) (116 aa) fasta scores: E(): 5.9e-16, 46.08% id in 115 aa.
       0.647
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
    0.599
glpD
Similar to Mycobacterium leprae glycerol-3-phosphate dehydrogenase GlpD or ML0713 or L308_C1_179 SW:GLPD_MYCLE (P53435) (585 aa) fasta scores: E(): 5.7e-116, 55.35% id in 560 aa, and to Escherichia coli aerobic glycerol-3-phosphate dehydrogenase GlpD or GlyD or B3426 SW:GLPD_ECOLI (P13035) (501 aa) fasta scores: E(): 2.4e-38, 33.67% id in 493 aa.
       0.548
glpF
Similar to Bacillus subtilis glycerol uptake facilitator protein GlpF SW:GLPF_BACSU (P18156) (274 aa) fasta scores: E(): 2.1e-23, 45.83% id in 240 aa; Belongs to the MIP/aquaporin (TC 1.A.8) family.
       0.530
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
     
 0.436
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.