STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2245Similar to Mycobacterium leprae putative phosphoglycerate mutase ML0079 TR:Q9CDC3 (EMBL:AL583917) (231 aa) fasta scores: E(): 4e-11, 33.64% id in 214 aa, and to Schizosaccharomyces pombe phosphoglycerate mutase Gpm1 or SPAC26F1.06 SW:PMGY_SCHPO (P36623) (211 aa) fasta scores: E(): 0.28, 24.4% id in 209 aa. (214 aa)    
Predicted Functional Partners:
pheA
Prephenate dehydratase; Similar to Corynebacterium glutamicum prephenate dehydratase PheA SW:PHEA_CORGL (P10341) (315 aa) fasta scores: E(): 8.6e-50, 52.75% id in 290 aa, and to Streptomyces coelicolor prephenate dehydratase SCD78.29c TR:Q9ZBX0 (EMBL:AL034355) (310 aa) fasta scores: E(): 6.4e-31, 39.63% id in 270 aa.
       0.791
DIP2248
Similar to Streptomyces coelicolor putative integral membrane protein SC10A9.14c TR:Q9AK90 (EMBL:AL583943) (275 aa) fasta scores: E(): 1.6e-17, 41.12% id in 248 aa.
 
    0.721
DIP2247
Putative amidase; Similar to Rhodococcus sp enantiomerase-selective amidase AmdA TR:Q53116 (EMBL:M74531) (462 aa) fasta scores: E(): 6.2e-15, 30.19% id in 414 aa, and to Mycobacterium smegmatis nicotinamidase/pyrazinamidase PzaA TR:Q9ZHK8 (EMBL:AF058285) (468 aa) fasta scores: E(): 6.4e-14, 30.55% id in 360 aa, and to Rhodococcus erythropolis amidase AmdA SW:AMID_RHOER (P22984) (520 aa) fasta scores: E(): 2.8e-11, 33.61% id in 238 aa; Belongs to the amidase family.
       0.678
DIP0856
Putative serine protease; Similar to Mycobacterium tuberculosis putative serine protease Rv0983 or MTV044.11 SWALL:O53896 (EMBL:AL021999) (464 aa) fasta scores: E(): 3.8e-46, 43.84% id in 406 aa, and to Brucella abortus probable serine protease do-like precursor DegP or HtrA SWALL:DEGP_BRUAB (SWALL:Q44597) (513 aa) fasta scores: E(): 7.6e-25, 44.56% id in 285 aa.
   
    0.563
cobIJ
Similar to Mycobacterium tuberculosis cobalamin biosynthesis protein [includes: precorrin-2 C20-methyltransferase; precorrin-3 methylase] CobIJ or Rv2066 or MT2126 or MTCY49.05 SWALL:COBI_MYCTU (SWALL:Q10677) (508 aa) fasta scores: E(): 3.6e-88, 50.7% id in 495 aa, C-terminal region to Rhodobacter capsulatus precorrin-3 methylase SWALL:O68097 (EMBL:AF010496) (245 aa) fasta scores: E(): 1.1e-34, 48.14% id in 243 aa, and N-terminal region to Pseudomonas aeruginosa precorrin-2 methyltransferase CobI or PA2904 SWALL:Q9HZU3 (EMBL:AE004716) (250 aa) fasta scores: E(): 1.4e-33, 43.3% id in 254 aa.
  
    0.478
prfA
Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
     
 0.475
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.