STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2253Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 34.5 kDa protein SCBAC25E3.11c TR:CAC44698 (EMBL:AL596251) (321 aa) fasta scores: E(): 1.1e-27, 36.17% id in 293 aa. (288 aa)    
Predicted Functional Partners:
DIP2254
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 29.9 kDa protein GlpQ1 or Rv3842c or MT3950 or MTCY01A6.27 TR:P96236 (EMBL:Z83864) (274 aa) fasta scores: E(): 1e-08, 36.84% id in 247 aa, and to Streptomyces coelicolor putative phosphodiesterase 2SCG4.06 TR:Q9K3Q8 (EMBL:AL360034) (227 aa) fasta scores: E(): 1.2e-08, 28.5% id in 228 aa.
       0.743
DIP1147
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 24.3 kDa protein SC7H2.13 SWALL:Q9S2K4 (EMBL:AL109732) (220 aa) fasta scores: E(): 1.4e-39, 50% id in 216 aa, and to Bacillus halodurans BH0355 protein SWALL:Q9KFW5 (EMBL:AP001508) (246 aa) fasta scores: E(): 1.3e-10, 28.51% id in 242 aa.
  
     0.676
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
       0.601
DIP0732
Hypothetical protein; No significant database matches.
  
     0.590
esxB
Very low similarity to Mycobacterium tuberculosis hypothetical 13.5 kDa protein Rv3445c or MTCY77.17c TR:O06262 (EMBL:Z95389) (125 aa) fasta scores: E(): 0.0007, 31.52% id in 92 aa; Belongs to the WXG100 family. CFP-10 subfamily.
  
     0.569
leuS
Similar to Escherichia coli leucyl-tRNA synthetase LeuS or B0642 SWALL:SYL_ECOLI (SWALL:P07813) (860 aa) fasta scores: E(): 1.9e-37, 37.53% id in 967 aa, and to Streptomyces coelicolor leucyl-tRNA synthetase LeuS SWALL:Q9RDL5 (EMBL:AL136518) (966 aa) fasta scores: E(): 1.6e-209, 59.93% id in 971 aa; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
     0.542
DIP1045
Hypothetical integral membrane protein; No database matches.
  
     0.536
DIP2049
Low similarity to Streptomyces coelicolor putative ABC transporter integral membrane protein SCE8.16c SWALL:Q9Z4W1 (EMBL:AL035654) (264 aa) fasta scores: E(): 1.7e-09, 26.37% id in 254 aa.
  
     0.515
DIP0598
Putative membrane protein; No significant database matches.
 
     0.513
DIP1352
Hypothetical protein; No significant database matches.
  
     0.511
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.