Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIP2266Conserved hypothetical protein; Similar to Streptomyces coelicolor putative Lsr2-like protein SCD25.12c SWALL:Q9RKK8 (EMBL:AL118514) (105 aa) fasta scores: E(): 1.1e-08, 39.04% id in 105 aa, and to Mycobacterium leprae Lsr2 protein precursor or ML0234 SWALL:LSR2_MYCLE (SWALL:P24094) (112 aa) fasta scores: E(): 2.4, 26.95% id in 115 aa. (105 aa)    
Predicted Functional Partners:
DIP2265
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 23.8 kDa protein Rv3850 or MTCY01A6.18C SWALL:P96227 (EMBL:Z83864) (218 aa) fasta scores: E(): 7.9e-15, 34.1% id in 217 aa.
       0.652
DIP2264
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 123.1 kDa protein Rv1251c or MT1290 or MTV006.23c SWALL:O50466 (EMBL:AL021006) (1139 aa) fasta scores: E(): 1.6, 26.47% id in 544 aa.
       0.572
DIP0004
Conserved hypothetical protein; Similar to Mycobacterium paratuberculosis hypothetical 17.5 kDa protein TR:Q9L7L4 (EMBL:AF222789) (166 aa) fasta scores: E(): 5.6e-18, 45.45% id in 143 aa.
  
     0.528
mihF
Integration host factor; Similar to Mycobacterium smegmatis integration host factor MihF SWALL:P96802 (EMBL:U75344) (105 aa) fasta scores: E(): 7.1e-21, 72.38% id in 105 aa, and to Mycobacterium tuberculosis hypothetical 20.8 kDa protein CY21B4.05 Rv1388 or MT1433 or MTCY21B4.05 SWALL:AAK45698 (EMBL:Z80108) (111 aa) fasta scores: E(): 3.8e-21, 74.75% id in 103 aa.
  
   
 0.511
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
   
 0.494
DIP1075
Similar to Mycobacterium leprae hypothetical protein ML1706 TR:Q9CBR6 (EMBL:AL583923) (337 aa) fasta scores: E(): 4.5e-19, 32.26% id in 313 aa, and to Mycobacterium tuberculosis CDC1551 vitamin-b12 independent methionine synthase family protein MT3095 TR:AAK47424 (EMBL:AE007129) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa, and to Mycobacterium tuberculosis hypothetical 34.2 kDa protein Rv3015c or MTV012.29C TR:O53262 (EMBL:AL021287) (337 aa) fasta scores: E(): 1.4e-18, 31.94% id in 313 aa.
  
     0.489
DIP2263
Similar to Mycobacterium tuberculosis putative membrane protein Rv2181 or MTV021.14 SWALL:O53515 (EMBL:AL021957) (427 aa) fasta scores: E(): 1.3e-33, 34.86% id in 370 aa.
 
     0.478
DIP0779
Conserved hypothetical protein; Similar to Mycobacterium leprae hypothetical 28.2 kDa protein ML2142 or MLCB57.29 TR:O33058 (EMBL:Z99494) (269 aa) fasta scores: E(): 5.4e-18, 43.55% id in 225 aa.
  
     0.466
DIP1921
Similar to Corynebacterium ammoniagenes hypothetical protein Orf3 TR:Q9RHY2 (EMBL:AB003158) (132 aa) fasta scores: E(): 4.5e-26, 61.15% id in 121 aa, and to Mycobacterium tuberculosis hypothetical protein Rv0807 TR:O06627 (EMBL:Z95618) (129 aa) fasta scores: E(): 2.3e-24, 57.48% id in 127 aa.
 
     0.432
DIP1394
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2750 TR:AAK47065 (EMBL:AE007105) (231 aa) fasta scores: E(): 3e-55, 59.3% id in 231 aa, and to Streptomyces coelicolor hypothetical 28.1 kDa protein Sc1B5.02 TR:O69830 (EMBL:AL023517) (243 aa) fasta scores: E(): 5.5e-48, 54.7% id in 223 aa.
  
     0.425
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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