STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2271Putative membrane protein; Similar to Streptomyces coelicolor hypothetical 8.0 kDa protein SCH69.22c SWALL:Q9XA12 (EMBL:AL079308) (69 aa) fasta scores: E(): 1.3e-05, 40% id in 50 aa. (50 aa)    
Predicted Functional Partners:
DIP2272
Possible sortase-like protein; Similar to Clostridium acetobutylicum sortase CAC0204 TR:AAK78186 (EMBL:AE007533) (194 aa) fasta scores: E(): 2.6e-06, 30.872% id in 149 aa, and weakly similar to Actinomyces naeslundii putative fimbria-associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 0.25, 32.941% id in 85 aa, and to Streptococcus pneumoniae TIGR4 sortase, putative SP0466 TR:AAK74626 (EMBL:AE007358) (279 aa) fasta scores: E(): 5.3, 25.000% id in 144 aa.
     
 0.932
DIP2273
Putative integral membrane protein; Similar to Mycobacterium paratuberculosis hypothetical 39.2 kDa protein SWALL:Q9L7M1 (EMBL:AF222789) (353 aa) fasta scores: E(): 1.2e-16, 32.69% id in 312 aa, and to Streptomyces coelicolor integral membrane protein SCH24.05 SWALL:O54569 (EMBL:Y16311) (431 aa) fasta scores: E(): 0.00015, 23.88% id in 448 aa. Note the overlap with downstream gene.
       0.689
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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