STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2274Similar to many eg. Streptomyces coelicolor putative transcriptional regulator SCD6.32c SWALL:Q9KZX2 (EMBL:AL353815) (200 aa) fasta scores: E(): 8.4e-15, 36.72% id in 177 aa. (208 aa)    
Predicted Functional Partners:
DIP2275
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 10.3 kDa protein Rv1861 or MTCY359.12c SWALL:P95154 (EMBL:Z83859) (101 aa) fasta scores: E(): 1.6e-10, 47.72% id in 88 aa, and to Escherichia coli transglycosylase associated protein YmgE or Tag or B1195 SWALL:TAG1_ECOLI (SWALL:P76011) (84 aa) fasta scores: E(): 2.5e-05, 38.82% id in 85 aa.
       0.609
DIP2276
Similar to many including predicted universal stress proteins eg. Mycobacterium tuberculosis hypothetical 30.9 kDa protein Rv2005c or MT2061 or MTCY39.12 SWALL:YK05_MYCTU (SWALL:Q10851) (295 aa) fasta scores: E(): 1.7e-32, 40.87% id in 296 aa, and to Mycobacterium tuberculosis CDC1551 universal stress protein family MT2698 SWALL:AAK47014 (EMBL:AE007102) (297 aa) fasta scores: E(): 1.7e-30, 36.73% id in 294 aa.
  
    0.511
DIP1844
Putative TetR-family regulatory protein; Similar to Rhizobium loti transcriptional regulator MLL3939 TR:Q98F48 (EMBL:AP003003) (209 aa) fasta scores: E(): 4.6e-12, 33.65% id in 208 aa, and to Pseudomonas aeruginosa probable transcriptional regulator PA1403 TR:Q9I3U1 (EMBL:AE004569) (210 aa) fasta scores: E(): 2e-05, 27.57% id in 214 aa.
  
     0.505
ispE
Putative kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
      
 0.477
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
      
 0.477
DIP2277
Similar to hypothetical proteins and proposed ribosomal pseudouridine synthases eg. Mycobacterium tuberculosis hypothetical 33.3 kDa protein Rv3300c or MT3399 or MTCI418A.02c SWALL:O07166 (EMBL:Z96070) (305 aa) fasta scores: E(): 6.3e-23, 45.74% id in 247 aa, and to Streptomyces coelicolor putative ribosomal pseudouridine synthase SCI41.08 SWALL:Q9RJ76 (EMBL:AL132648) (324 aa) fasta scores: E(): 1.9e-22, 40.69% id in 317 aa.
       0.468
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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