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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2279Putative ABC transport system, ATP-binding subunit; Similar to many eg. Bacillus halodurans ABC transporter BH3493 SWALL:Q9K777 (EMBL:AP001519) (283 aa) fasta scores: E(): 3.8e-18, 33.97% id in 209 aa, and to Bacillus subtilis hypothetical ABC transporter ATP-binding protein YhcG SWALL:YHCG_BACSU (SWALL:P54591) (232 aa) fasta scores: E(): 4.1e-12, 31.01% id in 216 aa. (289 aa)    
Predicted Functional Partners:
DIP2280
Similar to many eg. Bacillus halodurans transcriptional regulator BH3492 SWALL:Q9K778 (EMBL:AP001519) (129 aa) fasta scores: E(): 6.6e-15, 43.36% id in 113 aa.
 
    0.965
DIP2278
Putative integral membrane protein; No significant database matches. Lies downstream of a putative ABC transporter ATP-binding subunit.
       0.773
DIP2281
Conserved hypothetical protein; Similar to Streptomyces coelicolor hypothetical 44.0 kDa protein SC4G6.31c SWALL:Q9S2S7 (EMBL:AL096884) (403 aa) fasta scores: E(): 4.6e-09, 25.49% id in 459 aa.
       0.472
DIP2158
Pseudogene. Similar to C-terminus of Bacteriophage SP02 DNA polymerase L SWALL:DPOL_BPSP2 (SWALL:P06225) (648 aa) fasta scores: E(): 1.3e-34, 50.61% id in 245 aa, and to Xylella fastidiosa phage-related DNA polymerase XF0683 SWALL:Q9PFH5 (EMBL:AE003912) (726 aa) fasta scores: E(): 6e-19, 32.49% id in 277 aa. Presents a frameshift at residue 46.
  
  0.435
DIP2159
ABC transport protein; Similar to Yersinia enterocolitica lipoprotein inner membrane ABC-transporter, Irp6 TR:Q9X9I5 (EMBL:AJ132668) (600 aa) fasta scores: E(): 2.5e-43, 34.286% id in 560 aa, and to Streptomyces natalensis PimB protein TR:Q9EW97 (EMBL:AJ278573) (626 aa) fasta scores: E(): 3e-37, 32.519% id in 532 aa.
  
  0.403
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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