STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2294Similar to Mycobacterium smegmatis penicillin-binding protein 1 PonA SWALL:Q9F9V7 (EMBL:AF165523) (715 aa) fasta scores: E(): 4.1e-105, 51.23% id in 689 aa, and to Bacillus subtilis penicillin-binding protein 1A/1B PonA SWALL:PBPA_BACSU (SWALL:P39793) (914 aa) fasta scores: E(): 1.4e-32, 29.44% id in 720 aa. (726 aa)    
Predicted Functional Partners:
DIP2292
Putative membrane protein; No significant database matches.
     
 0.820
repA
Putative IS element transposase (pseudogene); Pseudogene. Similar to although shorter in its N-terminal region than Shigella flexneri putative transposase for IS110 S0128 SWALL:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 1.6e-18, 40.55% id in 254 aa, and similar to Streptomyces coelicolor putative IS element transposase SC3C8.17 SWALL:O69929 (EMBL:AL023861) (230 aa) fasta scores: E(): 7.9e-18, 45.61% id in 171 aa. Presents multiple frameshifts at residues 84, 125, 130, 145, 150 and 180.
    
 
 0.791
DIP1497
Putative secreted penicillin-binding protein; Similar to Mycobacterium tuberculosis penecillin binding protein Rv2864c or MTV003.10c TR:O33346 (EMBL:AL008883) (603 aa) fasta scores: E(): 1.9e-81, 42.81% id in 612 aa, and to Staphylococcus aureus beta-lactam-inducible penicillin-binding protein Pbp SW:PBP_STAAU (P07944) (670 aa) fasta scores: E(): 2.3e-07, 21.04% id in 632 aa.
  
 
 
 0.769
ftsI
Putative penicillin-binding (cell division related) protein; Similar to Corynebacterium glutamicum penicillin-binding protein FtsI TR:Q9FAD4 (EMBL:AB041009) (704 aa) fasta scores: E(): 3.1e-122, 59.38% id in 677 aa, and to Streptomyces coelicolor FtsI TR:Q9Z5V7 (EMBL:AF123319) (651 aa) fasta scores: E(): 2e-42, 32.24% id in 611 aa.
  
 
 
 0.763
DIP2295
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.0 kDa protein Rv0049 or MT0055 or MTCY21D4.12 SWALL:Y049_MYCTU (SWALL:P71706) (137 aa) fasta scores: E(): 1e-15, 47.52% id in 101 aa.
     
 0.761
DIP2293
Similar to Streptomyces coelicolor putative transmembrane protein SCH24.24 SWALL:Q9X8T8 (EMBL:AL049826) (502 aa) fasta scores: E(): 7.8e-37, 36.2% id in 453 aa.
  
    0.755
pbpA
Similar to Mycobacterium leprae putative penicillin-binding protein PbpA or ML0018 TR:Q9CDE6 (EMBL:AL583917) (492 aa) fasta scores: E(): 1.3e-72, 45.9% id in 488 aa.
  
 
 
 0.751
ag84
Antigen 84; Similar to Corynebacterium glutamicum antigen 84 Wag31 TR:Q9L4H7 (EMBL:AJ242594) (365 aa) fasta scores: E(): 1.7e-21, 60.66% id in 361 aa, and to Mycobacterium leprae antigen 84 Ag84 or ML0922 SW:AG84_MYCLE (P46815) (266 aa) fasta scores: E(): 1.8e-14, 43.97% id in 332 aa, and to Mycobacterium tuberculosis antigen 84 Ag84 or Wag31 or Rv2145c or MT2204 or MTCY270.23 SW:AG84_MYCTU (P46816) (260 aa) fasta scores: E(): 6.3e-14, 44.27% id in 332 aa. Note: Contains three putative colied-coil regions (residues 84..131, 193..235, 248..273).
   
 
 0.705
DIP2297
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 31.9 kDa protein Rv2319c or MT2382 or MTCY3G12.15 SWALL:YN19_MYCTU (SWALL:P71893) (292 aa) fasta scores: E(): 4.3e-21, 28% id in 300 aa.
     
 0.703
DIP2005
Putative D-Ala D-Ala carboxypeptidase; Similar to Mycobacterium tuberculosis hypothetical 46.8 kDa protein Rv3627c or MT3729 or MTCY15C10.25 SWALL:AAK48090 (EMBL:Z95436) (461 aa) fasta scores: E(): 5.2e-11, 37.04% id in 440 aa, and to Escherichia coli penicillin-binding protein 4 precursor DacB or B3182 SWALL:PBP4_ECOLI (SWALL:P24228) (477 aa) fasta scores: E(): 4.4e-05, 26.55% id in 433 aa.
      
 0.670
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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