STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2295Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.0 kDa protein Rv0049 or MT0055 or MTCY21D4.12 SWALL:Y049_MYCTU (SWALL:P71706) (137 aa) fasta scores: E(): 1e-15, 47.52% id in 101 aa. (120 aa)    
Predicted Functional Partners:
DIP2297
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 31.9 kDa protein Rv2319c or MT2382 or MTCY3G12.15 SWALL:YN19_MYCTU (SWALL:P71893) (292 aa) fasta scores: E(): 4.3e-21, 28% id in 300 aa.
     
 0.955
DIP2292
Putative membrane protein; No significant database matches.
     
 0.948
DIP2293
Similar to Streptomyces coelicolor putative transmembrane protein SCH24.24 SWALL:Q9X8T8 (EMBL:AL049826) (502 aa) fasta scores: E(): 7.8e-37, 36.2% id in 453 aa.
 
     0.795
DIP2296
Similar to Mycobacterium tuberculosis CDC1551 transcriptional regulator, MarR family MT0048 SWALL:AAK44270 (EMBL:AE006918) (208 aa) fasta scores: E(): 1.9e-07, 34.72% id in 144 aa, and to Streptomyces coelicolor putative MarR-family transcriptional regulator SC6D11.20 SWALL:Q9L135 (EMBL:AL158061) (155 aa) fasta scores: E(): 4.7e-05, 33.05% id in 121 aa.
     
 0.781
DIP2294
Similar to Mycobacterium smegmatis penicillin-binding protein 1 PonA SWALL:Q9F9V7 (EMBL:AF165523) (715 aa) fasta scores: E(): 4.1e-105, 51.23% id in 689 aa, and to Bacillus subtilis penicillin-binding protein 1A/1B PonA SWALL:PBPA_BACSU (SWALL:P39793) (914 aa) fasta scores: E(): 1.4e-32, 29.44% id in 720 aa.
     
 0.763
DIP1078
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 23.0 kDa protein Rv3013 or MTV012.27 TR:O53260 (EMBL:AL021287) (218 aa) fasta scores: E(): 2.6e-27, 40.63% id in 219 aa, and to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT3093 TR:AAK47422 (EMBL:AE007128) (240 aa) fasta scores: E(): 2.8e-27, 40.63% id in 219 aa, and to Mycobacterium leprae hypothetical 24.4 kDa protein MLCB637.11c TR:O33103 (EMBL:Z99263) (230 aa) fasta scores: E(): 1.3e-26, 40.18% id in 219 aa, and to Mycobacterium leprae hypothetical protein ML1704 TR:Q9CBR7 (EMB [...]
  
     0.754
DIP2282
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis 35 kDa protein Rv2744c or MT2815 or MTV002.09c SWALL:35KD_MYCTU (SWALL:P31511) (270 aa) fasta scores: E(): 8.4e-29, 45.52% id in 257 aa.
  
     0.717
DIP1455
Conserved hypothetical protein; Similar in its full length to Mycobacterium tuberculosis 35 kDa protein Rv2744c or MT2815 or MTV002.09c SW:35KD_MYCTU (P31511) (270 aa) fasta scores: E(): 1.2e-51, 75.8% id in 248 aa, N-terminal region to Mycobacterium leprae B2235_C2_187 MLCB33.06c TR:Q49840 (EMBL:U00019) (167 aa) fasta scores: E(): 2.9e-27, 72.1% id in 147 aa, and C-terminal region to Mycobacterium leprae B2235_C3_214 MLCB33.05c TR:Q49845 (EMBL:U00019) (114 aa) fasta scores: E(): 3.4e-12, 58.18% id in 110 aa.
  
     0.712
DIP2299
Putative integral membrane protein; No significant database matches.
       0.672
DIP1617
Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
  
     0.660
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: medium (44%) [HD]