Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP2296Similar to Mycobacterium tuberculosis CDC1551 transcriptional regulator, MarR family MT0048 SWALL:AAK44270 (EMBL:AE006918) (208 aa) fasta scores: E(): 1.9e-07, 34.72% id in 144 aa, and to Streptomyces coelicolor putative MarR-family transcriptional regulator SC6D11.20 SWALL:Q9L135 (EMBL:AL158061) (155 aa) fasta scores: E(): 4.7e-05, 33.05% id in 121 aa. (150 aa)    
Predicted Functional Partners:
DIP2297
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 31.9 kDa protein Rv2319c or MT2382 or MTCY3G12.15 SWALL:YN19_MYCTU (SWALL:P71893) (292 aa) fasta scores: E(): 4.3e-21, 28% id in 300 aa.
 
   
 0.904
DIP2299
Putative integral membrane protein; No significant database matches.
       0.801
DIP2295
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 15.0 kDa protein Rv0049 or MT0055 or MTCY21D4.12 SWALL:Y049_MYCTU (SWALL:P71706) (137 aa) fasta scores: E(): 1e-15, 47.52% id in 101 aa.
     
 0.758
DIP2298
Putative oxidoreductase; Similar to Bacillus subtilis hypothetical oxidoreductase YoxD SWALL:YOXD_BACSU (SWALL:P14802) (238 aa) fasta scores: E(): 2.2e-09, 28.57% id in 231 aa, and to Rhizobium sp putative short-chain type dehydrogenase/reductase SWALL:Y4EK_RHISN (SWALL:P55434) (248 aa) fasta scores: E(): 2.3e-09, 30% id in 210 aa.
     
 0.741
DIP2292
Putative membrane protein; No significant database matches.
     
 0.615
DIP2294
Similar to Mycobacterium smegmatis penicillin-binding protein 1 PonA SWALL:Q9F9V7 (EMBL:AF165523) (715 aa) fasta scores: E(): 4.1e-105, 51.23% id in 689 aa, and to Bacillus subtilis penicillin-binding protein 1A/1B PonA SWALL:PBPA_BACSU (SWALL:P39793) (914 aa) fasta scores: E(): 1.4e-32, 29.44% id in 720 aa.
     
 0.581
DIP2293
Similar to Streptomyces coelicolor putative transmembrane protein SCH24.24 SWALL:Q9X8T8 (EMBL:AL049826) (502 aa) fasta scores: E(): 7.8e-37, 36.2% id in 453 aa.
       0.542
DIP1082
Transmembrane efflux protein, major facilitator family; Similar to Mycobacterium tuberculosis CDC1551 drug transporter MT1289 TR:AAK45547 (EMBL:AE007004) (579 aa) fasta scores: E(): 9.3e-70, 43.87% id in 449 aa, and to Streptomyces coelicolor putative transmembrane efflux protein SCD82.12 TR:Q9L0L9 (EMBL:AL160431) (490 aa) fasta scores: E(): 5.7e-43, 31.79% id in 456 aa, and to Streptomyces glaucescens tetracenomycin C resistance and export protein TcmA SW:TCMA_STRGA (P39886) (538 aa) fasta scores: E(): 3.5e-39, 31.29% id in 425 aa; Belongs to the major facilitator superfamily.
 
   
 0.488
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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