STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2310Conserved hypothetical protein; Similar to N-terminal half of Pyrococcus abyssi hypothetical 48.8 kDa protein Pab1002 SWALL:Q9UYK0 (EMBL:AJ248287) (428 aa) fasta scores: E(): 0.081, 30.05% id in 193 aa. (192 aa)    
Predicted Functional Partners:
DIP2309
Putative DNA-binding protein; No significant database matches.
     0.988
DIP2311
Conserved hypothetical protein; Similar to Deinococcus radiodurans ATP-dependent DNA helicase RecG-related protein DR2199 SWALL:Q9RSC6 (EMBL:AE002053) (596 aa) fasta scores: E(): 1.1e-09, 27.17% id in 574 aa, and to Thiobacillus ferrooxidans ATP-dependent DNA helicase RecG SWALL:RECG_THIFE (SWALL:O50224) (652 aa) fasta scores: E(): 7.7e-05, 33.08% id in 133 aa.
 
     0.845
DIP2300
Putative DNA-binding protein; Regions similar to Pyrococcus abyssi hypothetical 32.8 kDa protein PAB0790 SWALL:Q9UZG6 (EMBL:AJ248286) (287 aa) fasta scores: E(): 1.4e-09, 27.45% id in 306 aa, and to Thiobacillus ferrooxidans ATP-dependent DNA helicase RecG SWALL:RECG_THIFE (SWALL:O50224) (652 aa) fasta scores: E(): 1.9e-07, 30.04% id in 223 aa.
  
     0.761
DIP0119
Conserved hypothetical protein; Similar to Deinococcus radiodurans ATP-dependent DNA helicase RecG-related protein DR2199 TR:Q9RSC6 (EMBL:AE002053) (596 aa) fasta scores: E(): 8.9e-13, 24.04% id in 445 aa.
  
     0.695
DIP2312
Putative type I restriction/modification system protein; Subunit R is required for both nuclease and ATPase activities, but not for modification.
  
    0.585
DIP2313
Putative type I restriction/modification system DNA specificity protein; Similar to Lactococcus lactis HsdS subunit SWALL:O68173 (EMBL:AF013596) (395 aa) fasta scores: E(): 2.7e-13, 33.72% id in 172 aa, and to Streptococcus thermophilus putative type I S-subunit protein HsdS SWALL:O52188 (EMBL:AF027167) (412 aa) fasta scores: E(): 1.6e-12, 27.84% id in 334 aa.
  
    0.571
DIP2013
Similar to Actinomyces naeslundii fimbrial subunit type 2 precursor SW:FM2_ACTNA (P12616) (534 aa) fasta scores: E(): 4.4e-20, 28.827% id in 503 aa, and to Actinomyces naeslundii type-1 fimbrial major subunit precursor FimP TR:Q9X4D8 (EMBL:AF107019) (533 aa) fasta scores: E(): 8.5e-15, 27.432% id in 514 aa. Note: Contains a potential sortase anchor site (LPLTG) upstream of the C-terminal region transmembrane domain.
  
     0.475
DIP0238
Putative surface-anchored fimbrial subunit; Weak similarity to Actimomyces fimbrial associated protein. Note: Contains a potential sortase anchor site (LPKTG) upstream of the C-terminal region transmembrane domain.
  
     0.461
DIP0233
Similar to Actinomyces naeslundii putative fimbrial associated protein TR:O05996 (EMBL:U85709) (280 aa) fasta scores: E(): 4.5e-16, 40.000% id in 215 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 1.2, 26.923% id in 156 aa. Note: Also similar to DIP0236 (312 aa) E(): 5.7e-25; 45.342% identity in 322 aa overlap, DIP2224, DIP2012 and DIP2225.
  
     0.450
DIP0236
Similar to Actinomyces naeslundii putative fimbrial associated protein TR:O68213 (EMBL:AF019629) (365 aa) fasta scores: E(): 1.2e-31, 42.802% id in 257 aa, and to Staphylococcus aureus sortase SrtA TR:Q9S446 (EMBL:AF162687) (206 aa) fasta scores: E(): 0.094, 27.559% id in 127 aa. Note: Also similar to DIP0233 (329 aa) E(): 5.2e-25; 45.031% identity in 322 aa overlap. Note: Also similar to DIP2012, DIP2224 and DIP2225.
  
     0.450
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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