STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DIP2319Putative copper zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (200 aa)    
Predicted Functional Partners:
sodA
Manganese superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
   
 0.991
qcrB
Ubiquinol-cytochrome C reductase cytochrome B subunit; Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
    
 
 0.889
qcrA
Ubiquinol-cytochrome C reductase iron-sulfur protein; Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis; Belongs to the Rieske iron-sulfur protein family.
   
 
 0.873
DIP1501
Putative membrane protein; No significant database matches.
    
   0.866
dirA
Almost identical to previously sequenced Corynebacterium diphtheriae iron repressible polypeptide DirA TR:Q46025 (EMBL:U18620) (198 aa) fasta scores: E(): 8.8e-79, 98.99% id in 198 aa, and to Mycobacterium smegmatis alkyl hydroperoxide reductase C AhpC TR:Q57529 (EMBL:U43719) (195 aa) fasta scores: E(): 5.2e-52, 66.12% id in 186 aa.
   
 
 0.857
DIP2032
Putative protease; Similar to Pseudomonas aeruginosa probable protease PA4171 SWALL:Q9HWL0 (EMBL:AE004833) (187 aa) fasta scores: E(): 3.2e-25, 50.28% id in 175 aa, and to Pyrococcus furiosus protease I PfpI or PF1719 SWALL:PFPI_PYRFU (SWALL:Q51732) (166 aa) fasta scores: E(): 1.8e-19, 40.58% id in 170 aa.
  
 
 0.848
DIP0062
Putative heavy metal-associated transport protein; Similar to Deinococcus radiodurans conserved hypothetical protein DR2452 TR:Q9RRN6 (EMBL:AE002074) (68 aa) fasta scores: E(): 0.0038, 43.103% id in 58 aa, and to Streptococcus pyogenes putative copper chaperone-copper transport operon CopZ or SPY1714 TR:Q99YG6 (EMBL:AE006600) (67 aa) fasta scores: E(): 0.0065, 40.000% id in 60 aa, and to Pseudomonas syringae Plasmid pPaCu1 copper resistance operon ORFH protein TR:Q9KWM7 (EMBL:AB033420) (65 aa) fasta scores: E(): 0.025, 40.000% id in 60 aa, and to Candida albicans copper-transporting p- [...]
   
 0.824
DIP2285
Putative cation transport protein; Similar to Streptomyces coelicolor putative metal associated protein SCG20A.25 SWALL:Q9K3L5 (EMBL:AL360055) (77 aa) fasta scores: E(): 1.3e-05, 45.9% id in 61 aa, and to Helicobacter felis cop associated protein CopP SWALL:COPP_HELFE (SWALL:O32620) (66 aa) fasta scores: E(): 0.0074, 36.92% id in 65 aa.
   
 0.824
cat
Catalase; Similar to Onchocerca volvulus endobacterium catalase Cat SW:CATA_ONCVE (Q27710) (482 aa) fasta scores: E(): 8e-92, 52.24% id in 490 aa.
  
 0.739
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
   0.732
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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