STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2319Putative copper zinc superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (200 aa)    
Predicted Functional Partners:
qcrB
Ubiquinol-cytochrome C reductase cytochrome B subunit; Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
    
 
 0.988
DIP1501
Putative membrane protein; No significant database matches.
    
   0.986
qcrA
Ubiquinol-cytochrome C reductase iron-sulfur protein; Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis; Belongs to the Rieske iron-sulfur protein family.
    
 
 0.986
sodA
Manganese superoxide dismutase; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
   
 
 0.951
DIP0062
Putative heavy metal-associated transport protein; Similar to Deinococcus radiodurans conserved hypothetical protein DR2452 TR:Q9RRN6 (EMBL:AE002074) (68 aa) fasta scores: E(): 0.0038, 43.103% id in 58 aa, and to Streptococcus pyogenes putative copper chaperone-copper transport operon CopZ or SPY1714 TR:Q99YG6 (EMBL:AE006600) (67 aa) fasta scores: E(): 0.0065, 40.000% id in 60 aa, and to Pseudomonas syringae Plasmid pPaCu1 copper resistance operon ORFH protein TR:Q9KWM7 (EMBL:AB033420) (65 aa) fasta scores: E(): 0.025, 40.000% id in 60 aa, and to Candida albicans copper-transporting p- [...]
   
 0.922
DIP2285
Putative cation transport protein; Similar to Streptomyces coelicolor putative metal associated protein SCG20A.25 SWALL:Q9K3L5 (EMBL:AL360055) (77 aa) fasta scores: E(): 1.3e-05, 45.9% id in 61 aa, and to Helicobacter felis cop associated protein CopP SWALL:COPP_HELFE (SWALL:O32620) (66 aa) fasta scores: E(): 0.0074, 36.92% id in 65 aa.
   
 0.922
dirA
Almost identical to previously sequenced Corynebacterium diphtheriae iron repressible polypeptide DirA TR:Q46025 (EMBL:U18620) (198 aa) fasta scores: E(): 8.8e-79, 98.99% id in 198 aa, and to Mycobacterium smegmatis alkyl hydroperoxide reductase C AhpC TR:Q57529 (EMBL:U43719) (195 aa) fasta scores: E(): 5.2e-52, 66.12% id in 186 aa.
   
 
 0.859
ctaD
Cytochrome C oxidase polypeptide I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity).
    
 
 0.783
ctaE
Similar to Corynebacterium glutamicum cytochrome AA3 oxidase subunit III CtaE TR:Q9AEL8 (EMBL:AJ306418) (205 aa) fasta scores: E(): 9.9e-67, 81.95% id in 205 aa, and to Mycobacterium tuberculosis probable cytochrome C oxidase polypeptide III CtaE or Rv2193 or MT2249 or MTCY190.04 SW:COX3_MYCTU (Q10385) (203 aa) fasta scores: E(): 3.6e-47, 60% id in 205 aa.
    
   0.761
ctaF
Putative membrane protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
    
   0.761
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.