STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2323Similar to Streptomyces coelicolor putative ABC transport system ATP-binding protein SC10A9.09c SWALL:Q9AK95 (EMBL:AL583943) (251 aa) fasta scores: E(): 4.7e-31, 51.35% id in 222 aa. (221 aa)    
Predicted Functional Partners:
DIP2324
Similar to Streptomyces coelicolor putative ABC transport system transmembrane protein SC10A9.10c SWALL:Q9AK94 (EMBL:AL583943) (379 aa) fasta scores: E(): 4.3e-17, 38.94% id in 380 aa. Lies alongside a putative ABC transporter ATP-binding subunit.
 
 0.996
DIP0485
Putative ABC transport system integral membrane protein; Similar to Bacillus halodurans BH3121 protein TR:Q9K885 (EMBL:AP001517) (398 aa) fasta scores: E(): 4e-20, 33.33% id in 438 aa.
 
 0.983
DIP0870
Putative membrane protein; Similar to Staphylococcus aureus (strain N315) hypothetical protein SA2305 or SAV2517 TR:BAB58679 (EMBL:AP003137) (359 aa) fasta scores: E(): 1.3e-35, 32.55% id in 344 aa.
      
 0.842
DIP0449
Putative ABC transport system integral membrane protein; Low similarity to Staphylococcus aureus, ABC transporter VraE or SA2493 or SAV2702 TR:Q9KWJ6 (EMBL:AB035452) (626 aa) fasta scores: E(): 0.066, 21.03% id in 385 aa.
  
 
 0.707
DIP2325
Putative surface-anchored protein; No significant database matches. Note: Contains a potential sortase anchor site (LAETG) upstream of the C-terminal region transmembrane domain. Also similar to DIP0439, DIP1724, DIP0442 and DIP0443.
     
 0.676
DIP2322
Hypothetical protein; No significant database matches.
       0.603
chrS
Two-component system histidine kinase ChrS; Previously sequenced and described as Corynebacterium diphtheriae histidine kinase ChrS SWALL:Q9RPF0 (EMBL:AF161327) (417 aa) fasta scores: E(): 4e-136, 88.72% id in 417 aa. Similar to many eg. Streptomyces reticuli histidine autokinase SenS SWALL:Q9RIM1 (EMBL:Y14336) (398 aa) fasta scores: E(): 1.6e-21, 35.28% id in 411 aa.
  
    0.593
chrA
Two-component response regulator ChrA; Previously sequenced and described as Corynebacterium diphtheriae response regulator ChrA SWALL:Q9RPE9 (EMBL:AF161327) (199 aa) fasta scores: E(): 2.7e-67, 98.49% id in 199 aa. Similar to many eg. Streptomyces reticuli response regulatory protein SenR SWALL:Q9RIM0 (EMBL:Y14336) (217 aa) fasta scores: E(): 1.5e-28, 49.51% id in 204 aa.
       0.579
DIP0585
Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 1.2e-37, 45.13% id in 257 aa, and to Escherichia coli iron FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5e-32, 42.8% id in 250 aa.
 
   
0.553
tsaD
Putative endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
    0.532
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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