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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2325Putative surface-anchored protein; No significant database matches. Note: Contains a potential sortase anchor site (LAETG) upstream of the C-terminal region transmembrane domain. Also similar to DIP0439, DIP1724, DIP0442 and DIP0443. (879 aa)    
Predicted Functional Partners:
DIP0438
Putative secreted protein; C-terminal similar to Bacillus halodurans surface adhesin A precursor PsaA or BH0516 TR:Q9KFG3 (EMBL:AP001508) (300 aa) fasta scores: E(): 2.9e-14, 34.09% id in 176 aa; Belongs to the bacterial solute-binding protein 9 family.
 
   
 0.856
DIP0440
Similar to Deinococcus radiodurans manganese ABC transporter, ATP-binding protein, putative DR2284 TR:Q9RS43 (EMBL:AE002060) (239 aa) fasta scores: E(): 5.3e-25, 39.57% id in 235 aa.
 
   
 0.756
DIP0441
Putative membrane protein; Similar to Streptococcus gordonii challis 29 kDa membrane protein in psaA 5'region SW:P29K_STRGC (P42361) (278 aa) fasta scores: E(): 3.8e-28, 38.25% id in 264 aa.
 
   
 0.701
DIP2323
Similar to Streptomyces coelicolor putative ABC transport system ATP-binding protein SC10A9.09c SWALL:Q9AK95 (EMBL:AL583943) (251 aa) fasta scores: E(): 4.7e-31, 51.35% id in 222 aa.
     
 0.676
DIP0331
Conserved hypothetical protein; Similar to Klebsiella oxytoca YiaX1 TR:AAK69523 (EMBL:AF282849) (315 aa) fasta scores: E(): 4.4e-18, 31.94% id in 313 aa.
  
     0.550
chrS
Two-component system histidine kinase ChrS; Previously sequenced and described as Corynebacterium diphtheriae histidine kinase ChrS SWALL:Q9RPF0 (EMBL:AF161327) (417 aa) fasta scores: E(): 4e-136, 88.72% id in 417 aa. Similar to many eg. Streptomyces reticuli histidine autokinase SenS SWALL:Q9RIM1 (EMBL:Y14336) (398 aa) fasta scores: E(): 1.6e-21, 35.28% id in 411 aa.
       0.548
chrA
Two-component response regulator ChrA; Previously sequenced and described as Corynebacterium diphtheriae response regulator ChrA SWALL:Q9RPE9 (EMBL:AF161327) (199 aa) fasta scores: E(): 2.7e-67, 98.49% id in 199 aa. Similar to many eg. Streptomyces reticuli response regulatory protein SenR SWALL:Q9RIM0 (EMBL:Y14336) (217 aa) fasta scores: E(): 1.5e-28, 49.51% id in 204 aa.
       0.548
cas9
Conserved hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans- encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. [...]
  
     0.507
DIP2324
Similar to Streptomyces coelicolor putative ABC transport system transmembrane protein SC10A9.10c SWALL:Q9AK94 (EMBL:AL583943) (379 aa) fasta scores: E(): 4.3e-17, 38.94% id in 380 aa. Lies alongside a putative ABC transporter ATP-binding subunit.
       0.489
DIP0330
Conserved hypothetical protein; C-terminal region similar to Micromonospora viridifaciens sialidase precursor NedA SW:NANH_MICVI (Q02834) (647 aa) fasta scores: E(): 1.8e-23, 34.24% id in 403 aa.
  
     0.479
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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