Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DIP2328Conserved integral membrane protein; Similar to Clostridium acetobutylicum uncharacterized conserved membrane protein, similar to Mdr CAC0829 SWALL:AAK78805 (EMBL:AE007599) (308 aa) fasta scores: E(): 0.0003, 25.88% id in 170 aa, and has region in common with Enterococcus faecium protein VanZ SWALL:VANZ_ENTFC (SWALL:Q06242) (161 aa) fasta scores: E(): 0.19, 29.16% id in 96 aa. (181 aa)    
Predicted Functional Partners:
DIP1994
Hypothetical protein; Poor database matches. N-terminus is similar to the C-terminal region of Pseudomonas aeruginosa malonate decarboxylase alpha subunit PA0208 TR:Q9I6T0 (EMBL:AE004459) (554 aa) fasta scores: E(): 3.7, 32.31% id in 164 aa.
      
 0.692
DIP0565
Hypothetical protein; No significant database matches. High concentration of alanine, glycine and proline residues.
  
     0.676
DIP1674
Hypothetical protein; Very low similarity to Homo sapiens galactokinase GalK1 or GalK SW:GAL1_HUMAN (P51570) blast scores: E(): 3e-05, score: 51 24% id.
  
     0.619
DIP0651
Similar to Campylobacter jejuni hypothetical protein CJ0069 TR:Q9PJ50 (EMBL:AL139074) (343 aa) fasta scores: E(): 3e-85, 61.36% id in 352 aa.
 
     0.583
sepF
Conserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
     0.552
DIP2329
Conserved integral membrane protein; Weak but full length similarity to many eg. Clostridium acetobutylicum uncharacterized conserved membrane protein, YhgE B.subtilis ortholog CAC3589 SWALL:AAK81512 (EMBL:AE007855) (783 aa) fasta scores: E(): 1.6e-16, 23.62% id in 766 aa.
       0.532
DIP0555
Putative surface-anchored membrane protein; Very low similarity to Mycobacterium tuberculosis hypothetical protein Rv3448 or MTCY77.20 or MT3554 SWALL:O33354 (EMBL:Z95390) (467 aa) fasta scores: E(): 0.0016, 21.96% id in 478 aa. Note: Contains a putative sortase anchor site (LPNTG).
  
     0.529
DIP2370
Putative secreted protein; Weak but full length similarity to Mycobacterium tuberculosis hypothetical 83.9 kDa protein Rv3909 or MTCY15F10.02c TR:O05436 (EMBL:Z94121) (802 aa) fasta scores: E(): 8.4e-10, 25.54% id in 916 aa.
  
     0.489
DIP0989
Putative hydrolase; Similar to the N-terminal region of Pichia jadinii beta-D-fructofuranoside fructohydrolase Inv1 TR:O94224 (EMBL:Y12659) (533 aa) fasta scores: E(): 1.5e-09, 26.33% id in 300 aa, and to the C-terminal region of Pseudomonas mucidolens endo-inulinase TR:Q9RGC0 (EMBL:AF141320) (776 aa) fasta scores: E(): 3.6e-07, 21.77% id in 473 aa.
  
     0.467
DIP1501
Putative membrane protein; No significant database matches.
  
     0.455
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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