STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2329Conserved integral membrane protein; Weak but full length similarity to many eg. Clostridium acetobutylicum uncharacterized conserved membrane protein, YhgE B.subtilis ortholog CAC3589 SWALL:AAK81512 (EMBL:AE007855) (783 aa) fasta scores: E(): 1.6e-16, 23.62% id in 766 aa. (633 aa)    
Predicted Functional Partners:
DIP2328
Conserved integral membrane protein; Similar to Clostridium acetobutylicum uncharacterized conserved membrane protein, similar to Mdr CAC0829 SWALL:AAK78805 (EMBL:AE007599) (308 aa) fasta scores: E(): 0.0003, 25.88% id in 170 aa, and has region in common with Enterococcus faecium protein VanZ SWALL:VANZ_ENTFC (SWALL:Q06242) (161 aa) fasta scores: E(): 0.19, 29.16% id in 96 aa.
       0.532
DIP0118
Putative dehydrogenase; Similar to Thermus aquaticus NADH dehydrogenase Nox SW:NOX_THETH (Q60049) (205 aa) fasta scores: E(): 3.2e-07, 34.18% id in 196 aa.
  
    0.469
DIP0265
Putative nitroreductase; Similar to Escherichia coli oxygen-insensitive NADPH nitroreductase NfsA or MdaA or Mda18 or B0851 SW:NFSA_ECOLI (P17117) (240 aa) fasta scores: E(): 2e-23, 36.32% id in 223 aa; Belongs to the flavin oxidoreductase frp family.
  
    0.469
DIP2160
Modular polyketide synthase; Similar to Streptomyces verticillus polyketide synthase BlmVIII (bleomycin biosynthesis) TR:Q9FB25 (EMBL:AF210249) (1841 aa) fasta scores: E(): 1.3e-72, 27.240% id in 1931 aa, and to Streptomyces noursei nystatin biosynthesis polyketide synthase Nys TR:Q9L4W3 (EMBL:AF263912) (11096 aa) fasta scores: E(): 4e-71, 33.107% id in 882 aa, and to Amycolatopsis mediterranei rifamycin polyketide synthase TR:Q9F847 (EMBL:AF262754) (1265 aa) fasta scores: E(): 7.7e-61, 31.042% id in 902 aa.
  
 
 0.450
DIP1988
Hypothetical protein; No significant database matches to the full length CDS. N-terminus is similar to the N-terminal region of Streptomyces coelicolor insertion element IS110 hypothetical protein SC3C8.10 SW:YIS1_STRCO (P19780) (405 aa) fasta scores: E(): 8.1e-15, 42.33% id in 137 aa, and to Shigella flexneri putative transposase for IS110 S0128 TR:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 4.6e-14, 40.87% id in 137 aa.
  
  
 0.440
DIP2189
Putative polyketide synthase; Similar to Mycobacterium tuberculosis polyketide synthase PKS13 or Rv3800c or MTV026.05c TR:O53579 (EMBL:AL022076) (1733 aa) fasta scores: E(): 5.4e-109, 44.5% id in 1719 aa, and to Polyangium cellulosum soraphen polyketide synthase A SorA TR:Q9ADL6 (EMBL:U24241) (6315 aa) fasta scores: E(): 6.2e-101, 35.96% id in 1090 aa.
  
 
 0.409
DIP2248
Similar to Streptomyces coelicolor putative integral membrane protein SC10A9.14c TR:Q9AK90 (EMBL:AL583943) (275 aa) fasta scores: E(): 1.6e-17, 41.12% id in 248 aa.
  
    0.405
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.