STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2334Putative dihydroxyacetone kinase sununit; Similar to Streptomyces coelicolor hypothetical 34.3 kDa protein SC4G1.39c SWALL:Q9FC11 (EMBL:AL391039) (330 aa) fasta scores: E(): 3e-61, 56.62% id in 332 aa, and to Selenomonas ruminantium subspruminantium dihydroxyacetone kinase Dhak1 SWALL:AAK84068 (EMBL:AF297121) (329 aa) fasta scores: E(): 7.8e-61, 56.19% id in 331 aa, and to Lycopersicon esculentum putative 3,4-dihydroxy-2-butanone kinase DhbK SWALL:DHBK_LYCES (SWALL:O04059) (594 aa) fasta scores: E(): 2.6e-42, 45.64% id in 333 aa. Lies upstream of a Dhak2 homologue. (331 aa)    
Predicted Functional Partners:
DIP2335
Similar to Selenomonas ruminantium subspruminantium dihydroxyacetone kinase Dhak2 SWALL:AAG14892 (EMBL:AF297121) (207 aa) fasta scores: E(): 6.6e-25, 48.51% id in 202 aa, and to Escherichia coli protein YcgS or B1199 SWALL:YCGS_ECOLI (SWALL:P76014) (210 aa) fasta scores: E(): 2e-22, 43.12% id in 211 aa. Lies downstream of a Dhak1 homologue.
  
  0.999
DIP2336
Similar to but longer than a family of hypothetical proteins eg. Deinococcus radiodurans conserved hypothetical protein DRB0052 SWALL:Q9RZR3 (EMBL:AE001826) (133 aa) fasta scores: E(): 8.8e-10, 43.75% id in 128 aa, and to Staphylococcus aureus (strain N315) hypothetical protein SA0607 or SAV0652 SWALL:Q99VW9 (EMBL:AP003131) (120 aa) fasta scores: E(): 1.3e-09, 42.73% id in 117 aa.
 
 0.999
DIP1893
Hypothetical protein; Similar to Escherichia coli glycerol dehydrogenase GldA SW:GLDA_ECOLI (P32665) (367 aa) fasta scores: E(): 6.1e-21, 29% id in 331 aa, and to Streptococcus pneumoniae glycerol dehydrogenase SP0253 TR:AAK74432 (EMBL:AE007338) (362 aa) fasta scores: E(): 3e-22, 29.64% id in 361 aa.
  
 
 0.935
DIP0267
Putative regulatory protein; Similar to Bacillus subtilis deoxyribonucleoside regulator DeoR SW:DEOR_BACSU (P39140) (313 aa) fasta scores: E(): 6.6e-43, 42.9% id in 303 aa.
     0.885
glpD
Similar to Mycobacterium leprae glycerol-3-phosphate dehydrogenase GlpD or ML0713 or L308_C1_179 SW:GLPD_MYCLE (P53435) (585 aa) fasta scores: E(): 5.7e-116, 55.35% id in 560 aa, and to Escherichia coli aerobic glycerol-3-phosphate dehydrogenase GlpD or GlyD or B3426 SW:GLPD_ECOLI (P13035) (501 aa) fasta scores: E(): 2.4e-38, 33.67% id in 493 aa.
    
 0.820
gpsA
Similar to Mycobacterium tuberculosis glycerol-3-phosphate dehydrogenase GpsA or GpdA2 or Rv2982c or MT3060 or MTCY349.05 SWALL:GPDA_MYCTU (SWALL:P95113) (334 aa) fasta scores: E(): 8.7e-69, 59.27% id in 329 aa, and to Bacillus subtilis glycerol-3-phosphate dehydrogenase GpsA or GlyC SWALL:GPDA_BACSU (SWALL:P46919) (345 aa) fasta scores: E(): 2.1e-43, 40.78% id in 331 aa; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 
 0.808
DIP2337
Similar to Lactococcus lactis abortive phage resistance protein AbilI SWALL:O06042 (EMBL:U94520) (458 aa) fasta scores: E(): 7.4e-08, 26.39% id in 466 aa. Lies in DNA region of low GC content.
       0.452
DIP2338
Hypothetical protein; No significant database matches.
       0.416
DIP2333
Similar to Streptomyces coelicolor putative integral membrane protein SCJ21.17C SWALL:Q9S1Z0 (EMBL:AL109747) (516 aa) fasta scores: E(): 1e-112, 66.53% id in 523 aa, and to Bacillus halodurans Bh0223 protein SWALL:Q9KG89 (EMBL:AP001507) (432 aa) fasta scores: E(): 9e-41, 36.42% id in 431 aa.
       0.410
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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