STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2336Similar to but longer than a family of hypothetical proteins eg. Deinococcus radiodurans conserved hypothetical protein DRB0052 SWALL:Q9RZR3 (EMBL:AE001826) (133 aa) fasta scores: E(): 8.8e-10, 43.75% id in 128 aa, and to Staphylococcus aureus (strain N315) hypothetical protein SA0607 or SAV0652 SWALL:Q99VW9 (EMBL:AP003131) (120 aa) fasta scores: E(): 1.3e-09, 42.73% id in 117 aa. (222 aa)    
Predicted Functional Partners:
DIP2334
Putative dihydroxyacetone kinase sununit; Similar to Streptomyces coelicolor hypothetical 34.3 kDa protein SC4G1.39c SWALL:Q9FC11 (EMBL:AL391039) (330 aa) fasta scores: E(): 3e-61, 56.62% id in 332 aa, and to Selenomonas ruminantium subspruminantium dihydroxyacetone kinase Dhak1 SWALL:AAK84068 (EMBL:AF297121) (329 aa) fasta scores: E(): 7.8e-61, 56.19% id in 331 aa, and to Lycopersicon esculentum putative 3,4-dihydroxy-2-butanone kinase DhbK SWALL:DHBK_LYCES (SWALL:O04059) (594 aa) fasta scores: E(): 2.6e-42, 45.64% id in 333 aa. Lies upstream of a Dhak2 homologue.
 
 0.999
DIP2335
Similar to Selenomonas ruminantium subspruminantium dihydroxyacetone kinase Dhak2 SWALL:AAG14892 (EMBL:AF297121) (207 aa) fasta scores: E(): 6.6e-25, 48.51% id in 202 aa, and to Escherichia coli protein YcgS or B1199 SWALL:YCGS_ECOLI (SWALL:P76014) (210 aa) fasta scores: E(): 2e-22, 43.12% id in 211 aa. Lies downstream of a Dhak1 homologue.
 
 0.999
ptsI
Phosphoenolpyruvate:sugar phosphotransferase system enzyme I (PTS system); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.994
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
 
 
 0.920
glpD
Similar to Mycobacterium leprae glycerol-3-phosphate dehydrogenase GlpD or ML0713 or L308_C1_179 SW:GLPD_MYCLE (P53435) (585 aa) fasta scores: E(): 5.7e-116, 55.35% id in 560 aa, and to Escherichia coli aerobic glycerol-3-phosphate dehydrogenase GlpD or GlyD or B3426 SW:GLPD_ECOLI (P13035) (501 aa) fasta scores: E(): 2.4e-38, 33.67% id in 493 aa.
    
 0.897
gpsA
Similar to Mycobacterium tuberculosis glycerol-3-phosphate dehydrogenase GpsA or GpdA2 or Rv2982c or MT3060 or MTCY349.05 SWALL:GPDA_MYCTU (SWALL:P95113) (334 aa) fasta scores: E(): 8.7e-69, 59.27% id in 329 aa, and to Bacillus subtilis glycerol-3-phosphate dehydrogenase GpsA or GlyC SWALL:GPDA_BACSU (SWALL:P46919) (345 aa) fasta scores: E(): 2.1e-43, 40.78% id in 331 aa; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 
  0.810
DIP2332
Putative phosphotransferase system protein; Similar to Streptomyces coelicolor hypothetical 17.6 kDa protein SCJ21.18C SWALL:Q9S1Y9 (EMBL:AL109747) (170 aa) fasta scores: E(): 3e-29, 56.97% id in 172 aa, and to Escherichia coli unknown pentitol II, A component SgaA or B4195 or Z5804 or ECS5171 SWALL:PTXA_ECOLI (SWALL:P39303) (154 aa) fasta scores: E(): 1.3e-12, 39.82% id in 113 aa.
  
  
 0.730
DIP0656
Putative transcriptional regulatory protein; Similar to Streptomyces coelicolor probable lacI-family transcriptional regulator SCC57A.16 TR:Q9RDI2 (EMBL:AL136519) (347 aa) fasta scores: E(): 5.5e-32, 34.04% id in 326 aa, and to Bacillus megaterium glucose-resistance amylase regulator CcpA SW:CCPA_BACME (P46828) (332 aa) fasta scores: E(): 5.1e-24, 29.17% id in 329 aa.
   
 
 0.727
DIP1969
Putative LacI-family transcriptional regulator; Similar to Escherichia coli raffinose operon repressor RafR SW:RAFR_ECOLI (P21867) (335 aa) fasta scores: E(): 1.5e-08, 24.52% id in 367 aa, and to Mycobacterium tuberculosis hypothetical protein Rv3575c TR:P96857 (EMBL:Z92774) (359 aa) fasta scores: E(): 1.8e-50, 45.82% id in 371 aa.
   
 
 0.727
glpF
Similar to Bacillus subtilis glycerol uptake facilitator protein GlpF SW:GLPF_BACSU (P18156) (274 aa) fasta scores: E(): 2.1e-23, 45.83% id in 240 aa; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
  
 0.689
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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