STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2340Similar to members of a family of nucleoside hydrolases eg. Mycobacterium tuberculosis nucleoside hydrolase IunH or Rv3393 or MTV004.51 SWALL:O50418 (EMBL:AL009198) (308 aa) fasta scores: E(): 7.6e-27, 36.07% id in 316 aa, and to Crithidia fasciculata inosine-uridine preferring nucleoside hydrolase IunH SWALL:IUNH_CRIFA (SWALL:Q27546) (314 aa) fasta scores: E(): 2.7e-14, 28.07% id in 317 aa. (331 aa)    
Predicted Functional Partners:
DIP2341
Putative integral membrane transport protein; Similar to Escherichia coli O157:H7 putative transporter ECS3800 SWALL:BAB37223 (EMBL:AP002563) (192 aa) fasta scores: E(): 6e-15, 30.16% id in 179 aa. Lies alongside a putative ABC transporter ATP-binding subunit.
 
   0.803
rbsK
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
  
 0.740
DIP2339
Putative major secreted protein; Similar to a family of proteins members of which are part of the antigen 85 complex responsible for the high affinity of mycobacteria for fibronectin. Similar to Corynebacterium ammoniagenes surface layer protein A SlpA SWALL:BAB62413 (EMBL:AB055224) (358 aa) fasta scores: E(): 2.6e-18, 31.23% id in 317 aa, and to Mycobacterium tuberculosis antigen 85-A precursor FbpA or Mpt44 or Rv3804c or MT3911 or MTV026.09c SWALL:A85A_MYCTU (SWALL:P17944) (338 aa) fasta scores: E(): 4.4e-18, 32.14% id in 280 aa, and to Corynebacterium glutamicum PS1 protein precurso [...]
  
    0.570
DIP2342
Similar to Streptomyces coelicolor putative integral membrane transport protein SCE87.11 SWALL:Q9RKC7 (EMBL:AL132674) (253 aa) fasta scores: E(): 0.082, 26.54% id in 226 aa.
       0.550
DIP2343
Similar to Streptomyces coelicolor putative ABC transporter ATP-binding subunit SCC53.15 SWALL:Q9KXJ6 (EMBL:AL357591) (563 aa) fasta scores: E(): 1.9e-05, 26.87% id in 439 aa, and to Methanobacterium thermoautotrophicum cobalt transport ATP-binding protein CbiO SWALL:Q50801 (EMBL:X94292) (277 aa) fasta scores: E(): 0.00012, 30.4% id in 171 aa.
       0.497
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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