STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2341Putative integral membrane transport protein; Similar to Escherichia coli O157:H7 putative transporter ECS3800 SWALL:BAB37223 (EMBL:AP002563) (192 aa) fasta scores: E(): 6e-15, 30.16% id in 179 aa. Lies alongside a putative ABC transporter ATP-binding subunit. (252 aa)    
Predicted Functional Partners:
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.906
DIP2342
Similar to Streptomyces coelicolor putative integral membrane transport protein SCE87.11 SWALL:Q9RKC7 (EMBL:AL132674) (253 aa) fasta scores: E(): 0.082, 26.54% id in 226 aa.
 
     0.885
DIP1768
Conserved hypothetical protein; Similar to Streptomyces coelicolor putative ankyrin-like protein SC6D7.25 TR:Q9RKX3 (EMBL:AL133213) (134 aa) fasta scores: E(): 4.4e-23, 57.36% id in 129 aa, and to Campylobacter jejuni ankyrin-repeat containing protein Cj1386 TR:Q9PMR4 (EMBL:AL139078) (156 aa) fasta scores: E(): 1.2e-10, 39.66% id in 121 aa.
   
 0.839
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.836
betA
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
    
 0.830
DIP2340
Similar to members of a family of nucleoside hydrolases eg. Mycobacterium tuberculosis nucleoside hydrolase IunH or Rv3393 or MTV004.51 SWALL:O50418 (EMBL:AL009198) (308 aa) fasta scores: E(): 7.6e-27, 36.07% id in 316 aa, and to Crithidia fasciculata inosine-uridine preferring nucleoside hydrolase IunH SWALL:IUNH_CRIFA (SWALL:Q27546) (314 aa) fasta scores: E(): 2.7e-14, 28.07% id in 317 aa.
 
   0.803
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.782
glnB
Nitrogen regulatory protein; Similar to Corynebacterium glutamicum PII protein GlnB TR:Q9X705 (EMBL:AJ010319) (112 aa) fasta scores: E(): 3.4e-31, 73.21% id in 112 aa, and to Azospirillum brasilense nitrogen regulatory protein P-II GlnB SW:GLNB_AZOBR (P21193) (112 aa) fasta scores: E(): 5.2e-25, 57.14% id in 112 aa, and to Escherichia coli nitrogen regulatory protein P-II 1 GlnB or B2553 or Z3829 or ECS3419 or STY2808 SW:GLNB_ECOLI (P05826) (112 aa) fasta scores: E(): 2e-24, 59.82% id in 112 aa; Belongs to the P(II) protein family.
    
 
 0.750
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.746
rpoZ
Putative DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  0.737
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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