STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2346Conserved hypothetical protein; Similar to proteins from streptococci eg. Streptococcus pneumoniae hypothetical protein Sp0341 SWALL:AAK74515 (EMBL:AE007346) (494 aa) fasta scores: E(): 3.6e-101, 51.82% id in 492 aa, and to Streptococcus pyogenes hypothetical protein Spy1343 SWALL:Q99Z89 (EMBL:AE006572) (518 aa) fasta scores: E(): 8.2e-100, 50.9% id in 495 aa; Belongs to the UPF0371 family. (497 aa)    
Predicted Functional Partners:
DIP2347
Hypothetical protein; Weakly similar to Rhizobium meliloti hypothetical protein Smc02732 r02394 or smc02732 TR:CAC46973 (EMBL:AL591790) (134 aa) fasta scores: E(): 1.4, 32.92% id in 82 aa.
       0.588
DIP2348
Hypothetical protein; Weakly similar to Mycobacterium tuberculosis hypothetical 15.7 kDa protein Rv2011c precursor or MT2066 or MTCY39.06 SW:YK11_MYCTU (Q10846) (143 aa) fasta scores: E(): 5.2, 26.66% id in 135 aa.
       0.588
pta
Phosphate acetyltransferase; Highly similar in its C-terminal region to Corynebacterium glutamicum phosphate acetyltransferase Pta SWALL:PTA_CORGL (SWALL:P77844) (329 aa) fasta scores: E(): 6.9e-94, 78.22% id in 326 aa, similar to the C-terminal region of Mycobacterium tuberculosis phosphate acetyltransferase Pta or Rv0408 or MT0421 or MTCY22G10.04 SWALL:PTA_MYCTU (SWALL:P96254) (690 aa) fasta scores: E(): 4.8e-68, 48.67% id in 452 aa, and similar to the C-terminal region of Escherichia coli phosphate acetyltransferase Pta or B2297 SWALL:PTA_ECOLI (SWALL:P39184) (713 aa) fasta scores: [...]
      0.430
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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