STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2349Putative integral membrane transport protein; Similar to Treponema pallidum glutamate/aspartate transporter, putative tp0555 TR:O83566 (EMBL:AE001231) (396 aa) fasta scores: E(): 2.9e-33, 33.86% id in 375 aa; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (414 aa)    
Predicted Functional Partners:
DIP2350
Putative integral membrane protein; No significant database matches.
       0.700
DIP0747
Putative membrane protein; Similar to Neisseria gonorrhoeae putative efflux pump component MtrF TR:Q9RNX1 (EMBL:AF176821) (522 aa) fasta scores: E(): 2.4e-35, 40.03% id in 527 aa, and to Escherichia coli aminobenzoyl-glutamate transport protein AbgT or B1336 SW:ABGT_ECOLI (P46133) (510 aa) fasta scores: E(): 1.7e-28, 34.72% id in 527 aa.
  
     0.658
ptsG
Similar to Corynebacterium glutamicum PTS system, glucose-specific IIABC component PtsG SWALL:PTGA_CORGL (SWALL:Q45298) (674 aa) fasta scores: E(): 2.8e-59, 44.91% id in 688 aa, and to Staphylococcus xylosus PTS system, sucrose-specific IIBC component ScrA SWALL:PTSB_STAXY (SWALL:P51184) (480 aa) fasta scores: E(): 8e-26, 27.73% id in 494 aa.
  
  
 0.596
DIP1992
Sodium:dicarboxylate symporter family; C-terminal region is similar to Escherichia coli proton glutamate symport protein GltP SW:GLTP_ECOLI (P21345) (437 aa) fasta scores: E(): 2.5e-34, 29.25% id in 417 aa, and to the C-terminal region of Caulobacter crescentus sodium:dicarboxylate symporter family protein CC1104 TR:Q9A990 (EMBL:AE005788) (476 aa) fasta scores: E(): 1.4e-90, 57.93% id in 435 aa. Possible alternative translational start site; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
  
     0.596
trpE
Similar to Corynebacterium glutamicum anthranilate synthase component I TrpE SW:TRPE_CORGL (P06557) (518 aa) fasta scores: E(): 5.7e-128, 65.44% id in 518 aa, and to Escherichia coli anthranilate synthase component I trpE or b1264 SW:TRPE_ECOLI (P00895) (520 aa) fasta scores: E(): 6.3e-66, 47.44% id in 508 aa.
       0.550
trpG
Similar to Corynebacterium glutamicum anthranilate synthase component II TrpG SW:TRPG_CORGL (P06558) (208 aa) fasta scores: E(): 5.8e-52, 65.23% id in 210 aa.
       0.550
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
       0.543
trpC1
Similar to Corynebacterium glutamicum tryptophan biosynthesis protein TrpCF [includes: indole-3-glycerol phosphate synthase trpC SW:TRPC_CORGL (P06560) (474 aa) fasta scores: E(): 7.5e-121, 70.15% id in 459 aa, and to Escherichia coli tryptophan biosynthesis protein TrpCF [includes: indole-3-glycerol phosphate synthase TrpC or b1262 SW:TRPC_ECOLI (P00909) (452 aa) fasta scores: E(): 3.9e-58, 41.7% id in 482 aa. Note overlap with upstream gene suggesting possible downstream translational start codon; Belongs to the TrpF family.
       0.543
DIP2347
Hypothetical protein; Weakly similar to Rhizobium meliloti hypothetical protein Smc02732 r02394 or smc02732 TR:CAC46973 (EMBL:AL591790) (134 aa) fasta scores: E(): 1.4, 32.92% id in 82 aa.
       0.464
DIP2348
Hypothetical protein; Weakly similar to Mycobacterium tuberculosis hypothetical 15.7 kDa protein Rv2011c precursor or MT2066 or MTCY39.06 SW:YK11_MYCTU (Q10846) (143 aa) fasta scores: E(): 5.2, 26.66% id in 135 aa.
       0.464
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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