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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2350Putative integral membrane protein; No significant database matches. (190 aa)    
Predicted Functional Partners:
DIP2349
Putative integral membrane transport protein; Similar to Treponema pallidum glutamate/aspartate transporter, putative tp0555 TR:O83566 (EMBL:AE001231) (396 aa) fasta scores: E(): 2.9e-33, 33.86% id in 375 aa; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.685
trpC1
Similar to Corynebacterium glutamicum tryptophan biosynthesis protein TrpCF [includes: indole-3-glycerol phosphate synthase trpC SW:TRPC_CORGL (P06560) (474 aa) fasta scores: E(): 7.5e-121, 70.15% id in 459 aa, and to Escherichia coli tryptophan biosynthesis protein TrpCF [includes: indole-3-glycerol phosphate synthase TrpC or b1262 SW:TRPC_ECOLI (P00909) (452 aa) fasta scores: E(): 3.9e-58, 41.7% id in 482 aa. Note overlap with upstream gene suggesting possible downstream translational start codon; Belongs to the TrpF family.
       0.624
trpE
Similar to Corynebacterium glutamicum anthranilate synthase component I TrpE SW:TRPE_CORGL (P06557) (518 aa) fasta scores: E(): 5.7e-128, 65.44% id in 518 aa, and to Escherichia coli anthranilate synthase component I trpE or b1264 SW:TRPE_ECOLI (P00895) (520 aa) fasta scores: E(): 6.3e-66, 47.44% id in 508 aa.
       0.599
trpG
Similar to Corynebacterium glutamicum anthranilate synthase component II TrpG SW:TRPG_CORGL (P06558) (208 aa) fasta scores: E(): 5.8e-52, 65.23% id in 210 aa.
       0.599
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
       0.587
trpB1
Tryptophan synthase beta chain TrpB1; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.466
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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