STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2369Conserved hypothetical protein; Extensive (but not full length) similarity to Mycobacterium tuberculosis hypothetical 27.1 kDa protein Rv3908 or MTCY15f10.03C TR:O05437 (EMBL:Z94121) (248 aa) fasta scores: E(): 2.3e-25, 47.39% id in 211 aa. Has a hydrophilic N-terminal region; Belongs to the Nudix hydrolase family. (290 aa)    
Predicted Functional Partners:
DIP2370
Putative secreted protein; Weak but full length similarity to Mycobacterium tuberculosis hypothetical 83.9 kDa protein Rv3909 or MTCY15F10.02c TR:O05436 (EMBL:Z94121) (802 aa) fasta scores: E(): 8.4e-10, 25.54% id in 916 aa.
 
   
 0.905
DIP2365
Similar to Bacillus subtilis branched-chain amino acid transport protein AzlD SW:AZLD_BACSU (O07923) (110 aa) fasta scores: E(): 8.2e-05, 36.27% id in 102 aa.
       0.687
DIP2366
Similar to Bacillus subtilis branched-chain amino acid transport protein AzlC SW:AZLC_BACSU (O07942) (254 aa) fasta scores: E(): 4.2e-14, 29.38% id in 211 aa.
       0.687
DIP2367
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 21.8 kDa protein Rv0038 or MT0043 or MTCY10h4.38 SW:Y038_MYCTU (P71608) (202 aa) fasta scores: E(): 4.4e-28, 43.64% id in 181 aa; Belongs to the UPF0301 (AlgH) family.
       0.687
DIP2368
Putative tRNA nucleotidyltransferase; Similar to a family of proteins from both prokaryotes and eukaryotes and including poly A polymerases and tRNA nucleotidyl transferases. Since prokaryotes don't generally have poly A tailed mRNAs the prokaryotic proteins are likely to be RNA nucleotidyl transferases. Similar to Mycobacterium tuberculosis PcnA or Rv3907c or MTCY15F10.04 TR:O05438 (EMBL:Z94121) (480 aa) fasta scores: E(): 3.5e-119, 64.61% id in 472 aa, and to Streptomyces coelicolor putative RNA nucleotidyltransferase SCH24.18 TR:Q9X8T2 (EMBL:AL049826) (483 aa) fasta scores: E(): 1.3 [...]
       0.687
DIP2371
Putative conserved integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 123.6 kDa protein Rv3910 or MTCY15F10.01c or MTV028.01 TR:O05435 (EMBL:Z94121) (1184 aa) fasta scores: E(): 1.1e-83, 35.58% id in 1200 aa, and to Rhizobium tropici virulence factor MviN homolog SW:MVIN_RHITR (O05467) (533 aa) fasta scores: E(): 5.7e-15, 23.87% id in 553 aa.
       0.678
DIP2372
Similar to Pseudomonas fluorescens alternative sigma factor AlgU TR:AAK94006 (EMBL:AF399758) (193 aa) fasta scores: E(): 8.1e-12, 30.1% id in 186 aa, and to Pseudomonas aeruginosa RNA polymerase sigma-H factor AlgU or AlgT or PA0762 SW:RPSH_PSEAE (Q06198) (193 aa) fasta scores: E(): 1.8e-11, 29.03% id in 186 aa; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.561
DIP2375
Putative hydrolase; Similar to Mycobacterium tuberculosis putative hydrolase CwlM or Rv3915 or MTV028.06 TR:O53593 (EMBL:AL021426) (406 aa) fasta scores: E(): 5.4e-78, 52.38% id in 399 aa, and to Bacillus subtilis N-acetylmuramoyl-L-alanine amidase CwlB precursor or LytC SW:CWLB_BACSU (Q02114) (496 aa) fasta scores: E(): 2.8e-07, 25.62% id in 199 aa.
 
     0.551
DIP1409
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis CDC1551 conserved hypothetical protein MT2781 TR:AAK47097 (EMBL:AE007107) (82 aa) fasta scores: E(): 1.4e-17, 65.78% id in 76 aa, and to Mycobacterium leprae U1764c ML1016 TR:Q49984 (EMBL:U15181) (107 aa) fasta scores: E(): 2.8e-16, 65.78% id in 76 aa.
  
     0.516
trxB
Thioredoxin reductase; Similar to Mycobacterium smegmatis thioredoxin reductase TrxB SW:TRXB_MYCSM (O30973) (311 aa) fasta scores: E(): 3.1e-72, 64.82% id in 307 aa.
     
 0.501
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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