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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIP2375Putative hydrolase; Similar to Mycobacterium tuberculosis putative hydrolase CwlM or Rv3915 or MTV028.06 TR:O53593 (EMBL:AL021426) (406 aa) fasta scores: E(): 5.4e-78, 52.38% id in 399 aa, and to Bacillus subtilis N-acetylmuramoyl-L-alanine amidase CwlB precursor or LytC SW:CWLB_BACSU (Q02114) (496 aa) fasta scores: E(): 2.8e-07, 25.62% id in 199 aa. (402 aa)    
Predicted Functional Partners:
trxA
Thioredoxin; Similar to Mycobacterium smegmatis thioredoxin TrxA SW:THIO_MYCSM (O30974) (112 aa) fasta scores: E(): 5.8e-18, 48.14% id in 108 aa; Belongs to the thioredoxin family.
   
   0.817
trxB
Thioredoxin reductase; Similar to Mycobacterium smegmatis thioredoxin reductase TrxB SW:TRXB_MYCSM (O30973) (311 aa) fasta scores: E(): 3.1e-72, 64.82% id in 307 aa.
  
    0.790
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
   
 0.772
DIP1281
Putative invasion protein; Similar to Mycobacterium tuberculosis hypothetical 49.8 kDa protein Rv1477 or MT1524 or MTV007.24 SWALL:O53168 (EMBL:AL021184) (472 aa) fasta scores: E(): 3.5e-21, 31.88% id in 577 aa, and C-terminal half similar to the whole length of Mycobacterium tuberculosis hypothetical invasion protein Inv1 SWALL:O33171 (EMBL:AF006054) (277 aa) fasta scores: E(): 1e-17, 39.5% id in 281 aa. Note: Contains two possible colied-coil region at residues 102..130 and 182..360.
 
  
 0.723
repA
Putative IS element transposase (pseudogene); Pseudogene. Similar to although shorter in its N-terminal region than Shigella flexneri putative transposase for IS110 S0128 SWALL:Q9AFS5 (EMBL:AF348706) (398 aa) fasta scores: E(): 1.6e-18, 40.55% id in 254 aa, and similar to Streptomyces coelicolor putative IS element transposase SC3C8.17 SWALL:O69929 (EMBL:AL023861) (230 aa) fasta scores: E(): 7.9e-18, 45.61% id in 171 aa. Presents multiple frameshifts at residues 84, 125, 130, 145, 150 and 180.
  
 
 0.708
DIP0834
Conserved hypothetical protein; Similar to Mycobacterium tuberculosis hypothetical 11.8 kDa protein Rv0948c or MT0975 or MTCY10D7.26 SW:Y948_MYCTU (P71562) (105 aa) fasta scores: E(): 1.6e-14, 62.35% id in 85 aa.
  
     0.705
DIP1617
Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
  
     0.677
DIP2371
Putative conserved integral membrane protein; Similar to Mycobacterium tuberculosis hypothetical 123.6 kDa protein Rv3910 or MTCY15F10.01c or MTV028.01 TR:O05435 (EMBL:Z94121) (1184 aa) fasta scores: E(): 1.1e-83, 35.58% id in 1200 aa, and to Rhizobium tropici virulence factor MviN homolog SW:MVIN_RHITR (O05467) (533 aa) fasta scores: E(): 5.7e-15, 23.87% id in 553 aa.
 
   
 0.677
DIP0749
Putative cell division protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
   
 0.652
DIP2105
Putative exported protein; Similar to the N-terminal portion of many from actinomycetes eg. Streptomyces coelicolor putative secreted protein SCE41.06c TR:Q9F2Q2 (EMBL:AL442120) (244 aa) fasta scores: E(): 7.5e-21, 65.74% id in 108 aa. Also full length similarity to others from actinomycetes eg. Streptomyces coelicolor putative membrane protein SC5C11.15 TR:Q9L157 (EMBL:AL158060) (121 aa) fasta scores: E(): 1.9e-14, 50.49% id in 101 aa.
 
   
 0.642
Your Current Organism:
Corynebacterium diphtheriae
NCBI taxonomy Id: 257309
Other names: C. diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC 13129, Corynebacterium diphtheriae NCTC13129
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