STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argSSimilar to Xylella fastidiosa arginyl-tRNA synthetase Xf0147 TR:Q9PGZ9 (EMBL:AE003868) (586 aa) fasta scores: E(): 4e-103, 52.700% id in 537 aa, and to Staphylococcus aureus subspaureus N315. arginyl-tRNA synthetase ArgS or Sa0564 TR:Q99W05 (EMBL:AP003131) (553 aa) fasta scores: E(): 9.9e-65, 40.603% id in 564 aa. (595 aa)    
Predicted Functional Partners:
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
  
  
 0.989
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
 
 0.986
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 0.942
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
  
 0.930
leuS
leucyl-tRNA synthetase; Similar to many e.g. Pseudomonas aeruginosa leucyl-tRNA synthetase LeuS, leuS or PA3987 SW:SYL_PSEAE (Q9HX33) (873 aa) fasta scores: E(): 0, 59.775% id in 890 aa; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 0.926
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
 
 0.925
BP0114
Putative exported protein; Similar to Pseudomonas aeruginosa hypothetical protein Pa5052 TR:Q9HUC7 (EMBL:AE004918) (231 aa) fasta scores: E(): 0.001, 28.807% id in 243 aa, and to Xylella fastidiosa hypothetical protein Xf0146 TR:Q9PH00 (EMBL:AE003868) (252 aa) fasta scores: E(): 6.8e-05, 29.167% id in 192 aa.
 
    0.924
lysS
Similar to Escherichia coli lysyl-tRNA synthetase LysS or HerC or AsuD or B2890 SW:SYK1_ECOLI (P13030) (504 aa) fasta scores: E(): 3.6e-115, 59.43% id in 498 aa, and to Neisseria meningitidis lysyl-tRNA synthetase LysS or Nma1638 TR:Q9JTT7 (EMBL:AL162756) (503 aa) fasta scores: E(): 1e-126, 62.32% id in 507 aa; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 0.906
glnS
Similar to Escherichia coli glutaminyl-tRNA synthetase GlnS SW:SYQ_ECOLI (P00962) (553 aa) fasta scores: E(): 9.5e-116, 53.64% id in 535 aa, and to Neisseria meningitidis glutaminyl-tRNA synthetase NMA1748 SW:SYQ_NEIMA (P57000) (562 aa) fasta scores: E(): 9.9e-119, 51.37% id in 584 aa.
  
 0.891
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
  
  
 0.870
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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