STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BP0982Similar to Caulobacter crescentus RNA pseudouridylate synthase, putative Cc0855 TR:Q9A9V6 (EMBL:AE005762) (255 aa) fasta scores: E(): 5.2e-38, 49.587% id in 242 aa, and to Neisseria meningitidis putative RNA-binding protein Nma1016 TR:Q9JV32 (EMBL:AL162754) (252 aa) fasta scores: E(): 1e-57, 66.116% id in 242 aa; Belongs to the pseudouridine synthase RsuA family. (243 aa)    
Predicted Functional Partners:
der
Putative GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.688
BP3002
Similar to Neisseria meningitidis hypothetical protein NMA2205 TR:Q9JSP1 (EMBL:AL162758) (635 aa) fasta scores: E(): 1.2e-70, 40.63% id in 598 aa, and to Neisseria meningitidis ribonuclease II-related protein NMB0282 TR:Q9K185 (EMBL:AE002385) (626 aa) fasta scores: E(): 9.7e-70, 40.13% id in 598 aa.
 
 
 0.671
cmk
Cytidylate kinase; Similar to Escherichia coli cytidylate kinase Cmk or MssA or B0910 or Z1256 or Ecs0993 SW:KCY_ECOLI (P23863) (227 aa) fasta scores: E(): 8.1e-40, 57.674% id in 215 aa, and identical to Bordetella bronchiseptica cytidylate kinase Cmk SW:KCY_BORBR (Q9RND6) (223 aa) fasta scores: E(): 1.5e-79, 98.655% id in 223 aa.
  
  
 0.658
efp
Putative elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
 
   
 0.626
ubiC
Conserved hypothetical protein (Pseudogene); Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family.
  
    0.623
BP1243
Conserved hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
  
  
 0.622
BP0369
Similar to Neisseria meningitidis putative nuclease Nma0348 or Nmb2082 TR:Q9JR99 (EMBL:AL162752) (259 aa) fasta scores: E(): 5e-63, 56.705% id in 261 aa, and to Streptomyces coelicolor putative exodeoxyribonuclease Sce87.25C TR:Q9RKB3 (EMBL:AL132674) (274 aa) fasta scores: E(): 2.3e-48, 47.388% id in 268 aa.
  
    0.619
BP2110
Similar to many e.g. Escherichia coli exodeoxyribonuclease III xthA or b1749 SW:EX3_ECOLI (P09030) (268 aa) fasta scores: E(): 1.2e-18, 36.842% id in 266 aa and Neisseria meningitidis putative exodeoxyribonuclease III NMA2086 TR:Q9JSY0 (EMBL:AL162758) (256 aa) fasta scores: E(): 2.4e-47, 50.382% id in 262 aa. It should be noted that at least one protein in this family, Pseudomonas aeruginosa crc or PA5332, TR:Q51380 (EMBL:U38241), appears to have no exonuclease activity and is unable to complement DNA-repair deficient E. coli.
  
    0.619
BP1434
Similar to Neisseria meningitidis putative RNA methyltransferase Nma1351 TR:Q9JUE8 (EMBL:AL162755) (261 aa) fasta scores: E(): 7.7e-33, 42.91% id in 261 aa, and to Synechocystis sp hypothetical tRNA/rRNA methyltransferase Slr1673 SW:YG73_SYNY3 (P74261) (274 aa) fasta scores: E(): 5.4e-18, 32.95% id in 264 aa.
 
 
 0.513
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
     0.492
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
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