STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BP1340Similar to Pseudomonas aeruginosa hypothetical protein Pa2156 TR:Q9I1V9 (EMBL:AE004642) (245 aa) fasta scores: E(): 2.2e-62, 63.93% id in 244 aa, and to Escherichia coli hypothetical protein YbhP or B0790 or Z1009 or Ecs0868 SW:YBHP_ECOLI (P75772) (253 aa) fasta scores: E(): 2.8e-53, 53.72% id in 255 aa. Also similar to BP0710, 37.801% identity (46.610% ungapped) in 291 aa overlap. (252 aa)    
Predicted Functional Partners:
clsB-2
Probable phospholipase; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
 
    0.990
ptxA
Pertussis toxin subunit 1 precursor; S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP- binding proteins from their membrane receptors.
    
   0.777
BP1842
Probable class-V aminotransferase; Similar to Escherichia coli selenocysteine lyase CsdB or SufS or B1680 SW:CSDB_ECOLI (P77444) (406 aa) fasta scores: E(): 1.3e-18, 29.57% id in 355 aa, and to Streptomyces capreolus capreomycin acetyltransferase Cac TR:Q53824 (EMBL:U13077) (359 aa) fasta scores: E(): 8.9e-38, 39.33% id in 361 aa.
  
   0.744
cvpA
Similar to Escherichia coli colicin V production protein CvpA or DedE or B2313 SW:CVPA_ECOLI (P08550) (162 aa) fasta scores: E(): 1.5e-10, 32.7% id in 159 aa, and to Pseudomonas aeruginosa hypothetical protein Pa3109 TR:Q9HZB0 (EMBL:AE004735) (180 aa) fasta scores: E(): 1.1e-13, 36.25% id in 160 aa.
  
    0.681
BP1413
Similar to Pseudomonas aeruginosa hypothetical protein Pa5052 TR:Q9HUC7 (EMBL:AE004918) (231 aa) fasta scores: E(): 0.00036, 35.71% id in 168 aa.
   
    0.617
BP1006
Probable glutathione S-transferase; Similar to Escherichia coli hypothetical Gst-like protein YfcF or B2301 SW:YFCF_ECOLI (P77544) (214 aa) fasta scores: E(): 1e-33, 52.683% id in 205 aa, and to Pseudomonas aeruginosa probable glutathione S-transferase Pa4401 TR:Q9HW05 (EMBL:AE004855) (211 aa) fasta scores: E(): 5.6e-08, 31.905% id in 210 aa.
  
    0.562
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
    0.533
BP2891
Conserved hypothetical protein; Similar to serveral including: Escherichia coli hypothetical Gst-like protein YibF or b3592 SW:YIBF_ECOLI (P32105) (202 aa) fasta scores: E(): 1.5e-26, 40.88% id in 203 aa, and to Escherichia coli O157:H7 EDL933 putative S-transferase YibF TR:AAG58736 (EMBL:AE005586) (202 aa) fasta scores: E(): 1.5e-26, 40.88% id in 203 aa.
  
    0.494
BP1406
Putative flagellar protein; Similar to Pseudomonas aeruginosa hypothetical protein Pa1473 TR:Q9I3N9 (EMBL:AE004576) (111 aa) fasta scores: E(): 2e-07, 43.18% id in 88 aa, and to Bacillus subtilis YlqH protein TR:O34867 (EMBL:AJ000975) (93 aa) fasta scores: E(): 2.7e-07, 42.68% id in 82 aa.
  
    0.470
psiF
Similar to Escherichia coli phosphate starvation-inducible protein PsiF precursor or B0384 SW:PSIF_ECOLI (P27295) (106 aa) fasta scores: E(): 0.00082, 51.220% id in 82 aa, and to Pseudomonas aeruginosa hypothetical protein Pa4874 TR:Q9HUT9 (EMBL:AE004901) (138 aa) fasta scores: E(): 2.9e-11, 50.562% id in 89 aa.
  
    0.469
Your Current Organism:
Bordetella pertussis
NCBI taxonomy Id: 257313
Other names: B. pertussis Tohama I, Bordetella pertussis Tohama I
Server load: low (16%) [HD]
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